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NCT01366131 · ClinicalTrials.gov registry record · Phase 2

Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease (NILE)

A Phase 2 study, sponsored by Genentech.

Completed
Registry status
Phase 2
Development phase
104
Enrollment target

NCT01366131 is a Phase 2 study that has completed, run by Genentech. The registered enrollment target is 104 participants.

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The verdict

NCT01366131, a Phase 2 study, has completed, sponsored by Genentech.

COMPLETED
Registry status
Phase 2
Development phase
104 participants
Enrollment target

Study Summary

This is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of MEGF0444A combined with paclitaxel + carboplatin + bevacizumab therapy in patients with histologically or cytologically documented inoperable, locally advanced, metastatic (Stage IV), or recurrent non-squamous NSCLC.

Interventions

  • DRUG placebo
  • DRUG carboplatin
  • DRUG bevacizumab
  • DRUG paclitaxel
  • DRUG MEGF0444A

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2011-06
Phase Phase 2

Sponsor

Genentech

332 total trials

What the Registry Record Tells You About NCT01366131

The ClinicalTrials.gov registry entry for NCT01366131 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 104 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which placebo is the first listed.

NCT01366131 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01366131 about?

NCT01366131 is a clinical study titled "Study Evaluating the Safety and Efficacy of MEGF0444A in Combination With Carboplatin, Paclitaxel and Bevacizumab in Patients With Advanced or Recurrent Non-Squamous Non-Small Cell Lung Cancer Who Have Not Received Prior Chemotherapy for Advanced Disease (NILE)". This is a Phase II, multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of MEGF0444A combined with paclitaxel + carboplatin + bevacizumab therapy in patients with histologically or cytologically documented inoperable, locally advanced, metasta...

What is the current status of trial NCT01366131?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 104 participants. The study started on 2011-06.

What interventions are being tested in trial NCT01366131?

The interventions under investigation include: placebo (DRUG), carboplatin (DRUG), bevacizumab (DRUG), paclitaxel (DRUG), MEGF0444A (DRUG).

Who is sponsoring clinical trial NCT01366131?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.