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NCT01363076 · ClinicalTrials.gov registry record · Phase 1

The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years

A Phase 1 study, sponsored by Egalet.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT01363076 is a Phase 1 study that has completed, run by Egalet. The registered enrollment target is 20 participants.

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The verdict

NCT01363076, a Phase 1 study, has completed, sponsored by Egalet.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This was an open-label PK study in pediatric subjects who had undergone general surgery. Each subject's study participation consisted of a screening visit, a single-dose treatment with intranasal ketorolac (IN) tromethamine, and a follow-up visit. Following surgery, subjects received IN ketorolac 15 mg (weight \< 50 kg) or 30 mg (weight \> or = 50 kg) when pain relief was indicated. For pain not relieved by the study drug, the subjects had access to an opioid analgesic administered by patient-controlled analgesia (PCA). Blood samples for pharmacokinetic analysis were obtained at specified time points following the dose of ketorolac.

Interventions

  • DRUG Ketorolac Tromethamine

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2007-06
Est. Completion 2008-05
Phase Phase 1

Sponsor

Egalet

5 total trials

What the Registry Record Tells You About NCT01363076

The ClinicalTrials.gov registry entry for NCT01363076 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Egalet, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Ketorolac Tromethamine is the first listed.

NCT01363076 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01363076 about?

NCT01363076 is a clinical study titled "The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years". This was an open-label PK study in pediatric subjects who had undergone general surgery. Each subject's study participation consisted of a screening visit, a single-dose treatment with intranasal ketorolac (IN) tromethamine, and a follow-up visit. Following surgery, subjects received IN ketorolac 1...

What is the current status of trial NCT01363076?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2007-06. Estimated completion is 2008-05.

What interventions are being tested in trial NCT01363076?

The interventions under investigation include: Ketorolac Tromethamine (DRUG).

Who is sponsoring clinical trial NCT01363076?

This trial is sponsored by Egalet, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.