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NCT01360632 · ClinicalTrials.gov registry record · Phase 3

Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)

A Phase 3 study, sponsored by Otsuka Pharmaceutical Development & Commercialization.

Completed
Registry status
Phase 3
Development phase
1,539
Enrollment target

NCT01360632 is a Phase 3 study that has completed, run by Otsuka Pharmaceutical Development & Commercialization. The registered enrollment target is 1,539 participants.

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The verdict

NCT01360632, a Phase 3 study, has completed, sponsored by Otsuka Pharmaceutical Development & Commercialization.

COMPLETED
Registry status
Phase 3
Development phase
1,539 participants
Enrollment target

Study Summary

To compare the effect of OPC-34712 (brexpiprazole) to the effect of placebo (an inactive substance) as add on treatment to an assigned FDA approved antidepressant treatment (ADT) in patients with Major Depressive Disorder who demonstrate an incomplete response to a prospective trial of the same assigned FDA approved ADT

Interventions

  • DRUG Placebo + ADT
  • DRUG OPC-34712 + ADT

Trial Details

FieldValue
Enrollment Target 1,539 participants
Start Date 2011-06
Est. Completion 2013-09
Phase Phase 3

What the Registry Record Tells You About NCT01360632

The ClinicalTrials.gov registry entry for NCT01360632 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 1,539 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Otsuka Pharmaceutical Development & Commercialization, which has 221 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo + ADT is the first listed.

NCT01360632 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01360632 about?

NCT01360632 is a clinical study titled "Study of the Safety and Efficacy of Two Fixed Doses of OPC-34712 as Adjunctive Therapy in the Treatment of Adults With Major Depressive Disorder (the Polaris Trial)". To compare the effect of OPC-34712 (brexpiprazole) to the effect of placebo (an inactive substance) as add on treatment to an assigned FDA approved antidepressant treatment (ADT) in patients with Major Depressive Disorder who demonstrate an incomplete response to a prospective trial of the same assi...

What is the current status of trial NCT01360632?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,539 participants. The study started on 2011-06. Estimated completion is 2013-09.

What interventions are being tested in trial NCT01360632?

The interventions under investigation include: Placebo + ADT (DRUG), OPC-34712 + ADT (DRUG).

Who is sponsoring clinical trial NCT01360632?

This trial is sponsored by Otsuka Pharmaceutical Development & Commercialization, which has 221 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.