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NCT01359566 · ClinicalTrials.gov registry record · Phase 3

Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis

A Phase 3 study of Multiple Sclerosis, sponsored by XenoPort.

Completed
Registry status
Phase 3
Development phase
228
Enrollment target
20
Study locations

NCT01359566 is a Phase 3 study of Multiple Sclerosis that has completed, run by XenoPort. The registered enrollment target is 228 participants, below the 584-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (61% lower). The trial reports 20 study locations across 12 states.

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The verdict

NCT01359566, a Phase 3 study of Multiple Sclerosis, has completed, sponsored by XenoPort.

COMPLETED
Registry status
Phase 3
Development phase
228 participants
Enrollment target
20
Study locations

Study Summary

To evaluate the efficacy of three doses of XP19986 (arbaclofen placarbil) compared to placebo for the treatment of spasticity in subjects with multiple sclerosis (MS).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Arbaclofen placarbil 15 mg BID
  • DRUG Arbaclofen placarbil 30 mg BID
  • DRUG Arbaclofen placarbil 45 mg BID

Study Locations (20)

Florida

  • XenoPort Clinical Site - Port Charlotte
  • XenoPort Clinical Site - Sarasota
  • XenoPort Clinical Site - St. Petersburg
  • XenoPort Clinical Site - Tampa

New York

  • XenoPort Clinical Site - Albany
  • XenoPort Clinical Site - Patchogue
  • XenoPort Clinical Site - Plainview

Arizona

  • XenoPort Clinical Site - Phoenix
  • XenoPort Clinical Site - Tucson

California

  • XenoPort Clinical Site - Berkeley
  • XenoPort Clinical Site - San Diego

Michigan

  • XenoPort Clinical Site - Bingham Farms
  • XenoPort Clinical Site - Detroit

Colorado

  • XenoPort Clinical Site - Denver

Illinois

  • XenoPort Clinical Site - Lake Barrington

Indiana

  • XenoPort Clinical Site - Indianapolis

Trial Details

FieldValue
Enrollment Target 228 participants
Start Date 2011-05
Est. Completion 2013-02
Phase Phase 3

Sponsor

XenoPort

19 total trials

What the Registry Record Tells You About NCT01359566

The ClinicalTrials.gov registry entry for NCT01359566 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 228 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 584-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (61% lower). The listed sponsor is XenoPort, which has 19 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT01359566 reports 20 study locations spanning 12 distinct geographic areas - top geographies include Florida, New York, Arizona.

Frequently Asked Questions

What is clinical trial NCT01359566 about?

NCT01359566 is a clinical study titled "Efficacy and Safety of Arbaclofen Placarbil in Subjects With Spasticity Due to Multiple Sclerosis". To evaluate the efficacy of three doses of XP19986 (arbaclofen placarbil) compared to placebo for the treatment of spasticity in subjects with multiple sclerosis (MS).

What is the current status of trial NCT01359566?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 228 participants. The study started on 2011-05. Estimated completion is 2013-02.

What conditions does trial NCT01359566 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT01359566?

The interventions under investigation include: Placebo (DRUG), Arbaclofen placarbil 15 mg BID (DRUG), Arbaclofen placarbil 30 mg BID (DRUG), Arbaclofen placarbil 45 mg BID (DRUG).

Who is sponsoring clinical trial NCT01359566?

This trial is sponsored by XenoPort, which has 19 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01359566 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Multiple Sclerosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.