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NCT01350947 · ClinicalTrials.gov registry record · Phase 2
A Study of 5-Azacitidine (Vidaza®) in Patients With Chronic Myelomonocytic Leukemia
A Phase 2 study of Chronic Myelomonocytic Leukemia, sponsored by University of Utah.
- Completed
- Registry status
- Phase 2
- Development phase
- 11
- Enrollment target
- 3
- Study locations
NCT01350947: Completed Phase 2 study of Chronic Myelomonocytic Leukemia, sponsored by University of Utah.
NCT01350947 is a Phase 2 study of Chronic Myelomonocytic Leukemia that has completed, run by University of Utah. The registered enrollment target is 11 participants, below the 89-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (88% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01350947, a Phase 2 study of Chronic Myelomonocytic Leukemia, has completed, sponsored by University of Utah.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 11 participants
- Enrollment target
- 3
- Study locations
Study Summary
The primary objective of this study is: Response to treatment will be evaluated according to the revised International Working Group (IWG) categories natural history, hematologic improvement and cytogenetic response1;2. The primary objective is: To determine the rate of complete hematologic response and hematologic improvement (according to IWG 2006 criteria) in CMML patients treated with 5-azacitidine.
Primary Outcome
Complete Hematologic Response is defined as: bone marrow evaluation shows \<= 5% myeloblasts with normal maturation of all cells lines; peripheral blood evaluation shows hemoglobin \>= 11 g/dL, neutrophils \>= 1000/mL, platelets \>= 100,000/mL, 0% blasts
Conditions Studied
Interventions
- DRUG 5-Azacitidine
Study Locations (3)
New York
- Roswell Park Cancer Institute - Buffalo
Oregon
- Oregon Health and Science University - Portland
Utah
- University of Utah - Salt Lake City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 11 participants |
| Start Date | 2011-04 |
| Est. Completion | 2014-09 |
| Phase | Phase 2 |
What the finished NCT01350947 record still lists
NCT01350947 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 11 participants, a relatively small participant target, below the 89-participant average among 73 other Chronic Myelomonocytic Leukemia trials with a reported enrollment target (88% lower).
The record links to 1 condition, with Chronic Myelomonocytic Leukemia appearing as the primary indexed condition, and to 1 intervention - of which 5-Azacitidine is the first listed.
NCT01350947 reports a single indexed study location in New York, Oregon, Utah.
Frequently Asked Questions
What is clinical trial NCT01350947 about?
NCT01350947 is a clinical study titled "A Study of 5-Azacitidine (Vidaza®) in Patients With Chronic Myelomonocytic Leukemia". The primary objective of this study is: Response to treatment will be evaluated according to the revised International Working Group (IWG) categories natural history, hematologic improvement and cytogenetic response1;2. The primary objective is: To determine the rate of complete hematologic respon...
What is the current status of trial NCT01350947?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 11 participants. The study started on 2011-04. Estimated completion is 2014-09.
What conditions does trial NCT01350947 study?
This clinical trial studies the following conditions: Chronic Myelomonocytic Leukemia.
What interventions are being tested in trial NCT01350947?
The interventions under investigation include: 5-Azacitidine (DRUG).
Who is sponsoring clinical trial NCT01350947?
This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01350947 being conducted?
This trial has 3 study locations across New York, Oregon, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01350947's enrollment target sits among peer trials
11 74th of 73 the lowest of 73 other Chronic Myelomonocytic Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Chronic Myelomonocytic Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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