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NCT01350349 · ClinicalTrials.gov registry record · NA
Home-delivered Intervention for Depressed, Cognitively Impaired Elders
A NA study, sponsored by Weill Medical College of Cornell University.
- Completed
- Registry status
- NA
- Development phase
- 134
- Enrollment target
NCT01350349: Completed NA study, sponsored by Weill Medical College of Cornell University.
NCT01350349 is a NA study that has completed, run by Weill Medical College of Cornell University. The registered enrollment target is 134 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01350349, a NA study, has completed, sponsored by Weill Medical College of Cornell University.
- COMPLETED
- Registry status
- NA
- Development phase
- 134 participants
- Enrollment target
Study Summary
Among older adults the combination of depression, cognitive impairment (memory problems), and disability contribute to a worsening of physical and mental health and to poor treatment outcomes. Antidepressants help fewer than 40% of depressed elders with memory problems achieve remission from their depression. Interventions involving talking therapy are underdeveloped and understudied. Therefore, this research study will test the efficacy of Problem Adaptation Therapy (PATH), a new home-delivered psychosocial intervention for elders with major depression, memory problems, and disability. PATH focuses on the subject's "ecosystem" (the patient, the caregiver, and the home-environment) and targets behavioral problems related to both depression and disability. PATH is delivered in a subject's home, where cognitively impaired, disabled elders face most of their difficulties. Local Home Delivered Meals programs will refer clients who have symptoms of depression and are interested in research. All participants will have an available caregiver (family, significant other, or professional) and will be randomized to 12 weekly sessions of PATH or Supportive Therapy, the current standard of care for talking therapy. The study will test whether home-delivered PATH is more effective than home-delivered Supportive Therapy in reducing the subjects' depression and disability and in increasing self-efficacy over the 12-week treatment period.
Primary Outcome
The primary objective is to compare the efficacy of Problem Adaptation Therapy vs. Supportive Therapy in reducing depressive symptoms over a 12-week treatment period among elders with major depression, cognitive impairment, and disability.
Interventions
- BEHAVIORAL Supportive Therapy
- BEHAVIORAL Problem Adaptation Therapy (PATH)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 134 participants |
| Start Date | 2011-04 |
| Est. Completion | 2017-02 |
| Phase | NA |
What the finished NCT01350349 record still lists
NCT01350349 is an interventional study that assigns participants to a tested intervention. The registered 134 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Supportive Therapy is the first listed.
NCT01350349 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01350349 about?
NCT01350349 is a clinical study titled "Home-delivered Intervention for Depressed, Cognitively Impaired Elders". Among older adults the combination of depression, cognitive impairment (memory problems), and disability contribute to a worsening of physical and mental health and to poor treatment outcomes. Antidepressants help fewer than 40% of depressed elders with memory problems achieve remission from their d...
What is the current status of trial NCT01350349?
This trial is currently completed. It is a NA study. The enrollment target is 134 participants. The study started on 2011-04. Estimated completion is 2017-02.
What interventions are being tested in trial NCT01350349?
The interventions under investigation include: Supportive Therapy (BEHAVIORAL), Problem Adaptation Therapy (PATH) (BEHAVIORAL).
Who is sponsoring clinical trial NCT01350349?
This trial is sponsored by Weill Medical College of Cornell University, which has 701 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01350349's enrollment target sits among peer trials
134 728th of 2000 higher than 1,272 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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