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NCT01340365 · ClinicalTrials.gov registry record · Phase 2

Tai Chi, Physiologic Complexity, and Healthy Aging

A Phase 2 study, sponsored by Harvard University Faculty of Medicine.

Completed
Registry status
Phase 2
Development phase
60
Enrollment target

NCT01340365: Completed Phase 2 study, sponsored by Harvard University Faculty of Medicine.

NCT01340365 is a Phase 2 study that has completed, run by Harvard University Faculty of Medicine. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01340365, a Phase 2 study, has completed, sponsored by Harvard University Faculty of Medicine.

COMPLETED
Registry status
Phase 2
Development phase
60 participants
Enrollment target

Study Summary

To evaluate the effects of Tai Chi-a mind-body exercise--on age-related loss of physiological complexity (using fractal and entropy based measures), and to understand the relationship between complexity, function and adaptability, we will conduct a two-arm prospective randomized clinical trial. Our overarching goal is to evaluate if six months of Tai Chi training, compared to a waitlist control receiving standard medical care, can enhance physiological complexity and adaptability in older Tai Chi-naïve adults. Secondary goals of the study are to characterize the relationship between complexity biomarkers, measures of function, and resilience. This pilot study will inform a future more definitive trial by providing information on recruitment and retention, compliance, dose-dependent effects, preliminary estimates of effect size, and the optimal biomarkers of complexity, function, and adaptive capacity.

Primary Outcome

Beat-to-beat variation measured using ECG for a 30 minute during seated quiet resting

Interventions

  • BEHAVIORAL Tai Chi
  • BEHAVIORAL Tai Chi Exercise

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2011-03
Est. Completion 2013-10
Phase Phase 2

What the finished NCT01340365 record still lists

NCT01340365 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 2 interventions - of which Tai Chi is the first listed.

NCT01340365 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01340365 about?

NCT01340365 is a clinical study titled "Tai Chi, Physiologic Complexity, and Healthy Aging". To evaluate the effects of Tai Chi-a mind-body exercise--on age-related loss of physiological complexity (using fractal and entropy based measures), and to understand the relationship between complexity, function and adaptability, we will conduct a two-arm prospective randomized clinical trial. Our ...

What is the current status of trial NCT01340365?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2011-03. Estimated completion is 2013-10.

What interventions are being tested in trial NCT01340365?

The interventions under investigation include: Tai Chi (BEHAVIORAL), Tai Chi Exercise (BEHAVIORAL).

Who is sponsoring clinical trial NCT01340365?

This trial is sponsored by Harvard University Faculty of Medicine, which has 9 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01340365's enrollment target sits among peer trials

60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01340365, the US trial registry maintained by the National Library of Medicine. NCT01340365 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.