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NCT01339910 · ClinicalTrials.gov registry record · Phase 3

Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)

A Phase 3 study, sponsored by Medical College of Wisconsin.

Terminated
Registry status
Phase 3
Development phase
272
Enrollment target

NCT01339910: Clinical Trial Phase 3 study, sponsored by Medical College of Wisconsin.

NCT01339910 is a Phase 3 study that was terminated before completion, run by Medical College of Wisconsin. The registered enrollment target is 272 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01339910, a Phase 3 study, was terminated before completion, sponsored by Medical College of Wisconsin.

TERMINATED
Registry status
Phase 3
Development phase
272 participants
Enrollment target

Study Summary

The study is designed as a Phase III, multicenter trial comparing outcomes after allogeneic hematopoietic stem cell transplantation (HCT) for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) between patients receiving myeloablative conditioning (MAC) versus reduced intensity conditioning (RIC) regimens.

Primary Outcome

Overall survival is defined as survival of death from any cause.

Interventions

  • DRUG Fludarabine and Busulfan
  • DRUG Fludarabine and Melphalan
  • DRUG Busulfan and Fludarabine
  • DRUG Cyclophosphamide and Total Body Irradiation
  • DRUG Busulfan and Cyclophosphamide

Trial Details

FieldValue
Enrollment Target 272 participants
Start Date 2011-06
Est. Completion 2017-10-16
Phase Phase 3
Medical College of Wisconsin

447 total trials

Why NCT01339910 stopped before completion

NCT01339910 is an interventional study that assigns participants to a tested intervention. The registered 272 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (65% lower).

The record links to 0 conditions, and to 5 interventions - of which Fludarabine and Busulfan is the first listed.

NCT01339910 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01339910 about?

NCT01339910 is a clinical study titled "Reduced Intensity Regimen vs Myeloablative Regimen for Myeloid Leukemia or Myelodysplastic Syndrome (BMT CTN 0901)". The study is designed as a Phase III, multicenter trial comparing outcomes after allogeneic hematopoietic stem cell transplantation (HCT) for acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) between patients receiving myeloablative conditioning (MAC) versus reduced intensity conditioni...

What is the current status of trial NCT01339910?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 272 participants. The study started on 2011-06. Estimated completion is 2017-10-16.

What interventions are being tested in trial NCT01339910?

The interventions under investigation include: Fludarabine and Busulfan (DRUG), Fludarabine and Melphalan (DRUG), Busulfan and Fludarabine (DRUG), Cyclophosphamide and Total Body Irradiation (DRUG), Busulfan and Cyclophosphamide (DRUG).

Who is sponsoring clinical trial NCT01339910?

This trial is sponsored by Medical College of Wisconsin, which has 447 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01339910's enrollment target sits among peer trials

272 1214th of 2000 higher than 785 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01339910, the US trial registry maintained by the National Library of Medicine. NCT01339910 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.