Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01336959 · ClinicalTrials.gov registry record · Phase 2
Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery
A Phase 2 study, sponsored by Mereo BioPharma.
- Terminated
- Registry status
- Phase 2
- Development phase
- 91
- Enrollment target
NCT01336959: Clinical Trial Phase 2 study, sponsored by Mereo BioPharma.
NCT01336959 is a Phase 2 study that was terminated before completion, run by Mereo BioPharma. The registered enrollment target is 91 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01336959, a Phase 2 study, was terminated before completion, sponsored by Mereo BioPharma.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 91 participants
- Enrollment target
Study Summary
This study will assess the safety and efficacy of BCT197 on acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass.
Primary Outcome
Median percent change from baseline in estimated Glomerular Filtration Rate (eGFR) at 48 hours postdose.
Interventions
- DRUG Placebo
- DRUG BCT197 Part A
- DRUG BCT197 Part B
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 91 participants |
| Start Date | 2011-09 |
| Est. Completion | 2013-11 |
| Phase | Phase 2 |
Why NCT01336959 stopped before completion
NCT01336959 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 91 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower).
The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.
NCT01336959 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01336959 about?
NCT01336959 is a clinical study titled "Safety & Efficacy of BCT197 in Patients Undergoing Cardiac Surgery". This study will assess the safety and efficacy of BCT197 on acute kidney injury in patients undergoing cardiac surgery with cardiopulmonary bypass.
What is the current status of trial NCT01336959?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 91 participants. The study started on 2011-09. Estimated completion is 2013-11.
What interventions are being tested in trial NCT01336959?
The interventions under investigation include: Placebo (DRUG), BCT197 Part A (DRUG), BCT197 Part B (DRUG).
Who is sponsoring clinical trial NCT01336959?
This trial is sponsored by Mereo BioPharma, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01336959's enrollment target sits among peer trials
91 771st of 2000 higher than 1,229 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02671448 · 91 participants · NA
Pilot Trial of Homebound Stem Cell Transplantation
- NCT04835857 · 91 participants
Comparison of Cuff-Less Wrist Wearable Blood Pressure Device to Cuff Based Blood Pressure Measuring Devices
- NCT05184842 · 91 participants · Phase 2
Metabolically Optimized, Non-cytotoxic Low Dose Weekly Decitabine/Venetoclax in MDS and AML
- NCT05685173 · 91 participants · Phase 1
A Trial to Study if REGN5837 in Combination With Odronextamab is Safe for Adult Participants With Aggressive B-cell Non-Hodgkin Lymphomas
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia