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NCT01334281 · ClinicalTrials.gov registry record
An In-vitro Standardization of B Cell Elispot Assays
A clinical trial, sponsored by Northwestern University.
- Terminated
- Registry status
- 19
- Enrollment target
NCT01334281: Clinical Trial study, sponsored by Northwestern University.
NCT01334281 is a clinical trial that was terminated before completion, run by Northwestern University. The registered enrollment target is 19 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01334281 was terminated before completion, sponsored by Northwestern University.
- TERMINATED
- Registry status
- 19 participants
- Enrollment target
Study Summary
This study is being done because the study doctor is trying to develop a new test which will help transplant doctors monitor patients with high panel reactive antibodies (PRA). The test would be used to monitor patients' PRA when doctors are trying to lower it through a process known as desensitization. Desensitization lowers high PRA levels and allows patients to receive transplants. This is a single center study to evaluate and optimize the use of a new laboratory test to detect and measure the immune system's functioning.
Primary Outcome
B cells will be tested for their ability to produce IgG and tetanus antibodies (as controls) and HLA specific antibodies corresponding to those detected by the flow PRA assay. In subjects not undergoing desensitization, 3 tubes (30 ml) of blood will be drawn twice (total of 60 ml blood taken) 8-12 weeks apart. In subjects undergoing desensitization 3 tubes (30 ml) of blood will be taken at 7 points; enrollment, anticipated midpoint of desensitization, prior to transplant, 3, 6, 12 and 24 Months
Interventions
- PROCEDURE Blood Draw
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2008-02 |
| Est. Completion | 2012-10 |
Why NCT01334281 stopped before completion
NCT01334281 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 19 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Blood Draw is the first listed.
NCT01334281 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01334281 about?
NCT01334281 is a clinical study titled "An In-vitro Standardization of B Cell Elispot Assays". This study is being done because the study doctor is trying to develop a new test which will help transplant doctors monitor patients with high panel reactive antibodies (PRA). The test would be used to monitor patients' PRA when doctors are trying to lower it through a process known as desensitizat...
What is the current status of trial NCT01334281?
This trial is currently terminated. The enrollment target is 19 participants. The study started on 2008-02. Estimated completion is 2012-10.
What interventions are being tested in trial NCT01334281?
The interventions under investigation include: Blood Draw (PROCEDURE).
Who is sponsoring clinical trial NCT01334281?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
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