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NCT01331551 · ClinicalTrials.gov registry record
Mesalamine and Reproductive Health Study
A clinical trial, sponsored by Harvard School of Public Health (HSPH).
- Completed
- Registry status
- 130
- Enrollment target
NCT01331551 is a clinical trial that has completed, run by Harvard School of Public Health (HSPH). The registered enrollment target is 130 participants.
The verdict
NCT01331551 has completed, sponsored by Harvard School of Public Health (HSPH).
- COMPLETED
- Registry status
- 130 participants
- Enrollment target
Study Summary
The purpose of this study is to investigate the relationship of high exposure to dibutyl phthalate (DBP) from the use of Asacol with clinical and intermediate markers of male fertility, including semen quality, sperm DNA damage, transcript profiles of sperm mRNA and sncRNAs, and reproductive hormones. Hypothesis 1: High exposure to DBP from the use of Asacol is associated with decreased sperm concentration and motility, and increased sperm DNA damage. Hypothesis 2: High exposure to DBP from the use of Asacol is associated with decreased serum testosterone, altered LH:testosterone ratio, and decreased inhibin-B. Hypothesis 3: High exposure to DBP from the use of Asacol is associated with altered transcript profiles of sperm mRNAs and sncRNAs.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 130 participants |
| Start Date | 2010-05 |
| Est. Completion | 2018-08 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01331551
The ClinicalTrials.gov registry entry for NCT01331551 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 130 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Harvard School of Public Health (HSPH), which has 40 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 0 interventions.
NCT01331551 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01331551 about?
NCT01331551 is a clinical study titled "Mesalamine and Reproductive Health Study". The purpose of this study is to investigate the relationship of high exposure to dibutyl phthalate (DBP) from the use of Asacol with clinical and intermediate markers of male fertility, including semen quality, sperm DNA damage, transcript profiles of sperm mRNA and sncRNAs, and reproductive hormone...
What is the current status of trial NCT01331551?
This trial is currently completed. The enrollment target is 130 participants. The study started on 2010-05. Estimated completion is 2018-08.
Who is sponsoring clinical trial NCT01331551?
This trial is sponsored by Harvard School of Public Health (HSPH), which has 40 total clinical trials registered on ClinicalTrials.gov.
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