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NCT01322243 · ClinicalTrials.gov registry record · NA
Effect of Metabolic State on Anxiety in Human Subjects
A NA study, sponsored by Rockefeller University.
- Terminated
- Registry status
- NA
- Development phase
- 10
- Enrollment target
NCT01322243: Clinical Trial NA study, sponsored by Rockefeller University.
NCT01322243 is a NA study that was terminated before completion, run by Rockefeller University. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01322243, a NA study, was terminated before completion, sponsored by Rockefeller University.
- TERMINATED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
Study Summary
In this study, we would like to explore the hypothesis that changes in metabolic state, induced by altering hormone levels and patterns of neural activity, affect the experience of anxiety in humans. We will also investigate if there is a link between high anxiety and higher caloric intake. Our aim is to characterize whether changes in current metabolic state systematically influence anxiety induced by a well established behavioral task known as the threat of shock. The neural regions activated by this behavioral task in healthy subjects have been well characterized. We have a priori regions of interest that include the insula, anterior cingulate cortex, hypothalamus, amygdala, and prefrontal cortex. As our primary outcome, we will assess neural activation with whole-brain functional magnetic resonance imaging to determine whether brain regions are differentially engaged when subjects experience anxiety across different metabolic states. We will correlate these changes with psychophysiological measures of anxiety and metabolic state.
Interventions
- OTHER Dietary manipulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2011-03 |
| Est. Completion | 2013-02 |
| Phase | NA |
Why NCT01322243 stopped before completion
NCT01322243 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Dietary manipulation is the first listed.
NCT01322243 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01322243 about?
NCT01322243 is a clinical study titled "Effect of Metabolic State on Anxiety in Human Subjects". In this study, we would like to explore the hypothesis that changes in metabolic state, induced by altering hormone levels and patterns of neural activity, affect the experience of anxiety in humans. We will also investigate if there is a link between high anxiety and higher caloric intake. Our aim ...
What is the current status of trial NCT01322243?
This trial is currently terminated. It is a NA study. The enrollment target is 10 participants. The study started on 2011-03. Estimated completion is 2013-02.
What interventions are being tested in trial NCT01322243?
The interventions under investigation include: Dietary manipulation (OTHER).
Who is sponsoring clinical trial NCT01322243?
This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01322243's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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