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NCT01309750 · ClinicalTrials.gov registry record
Small Bowel Transit Time in Clostridium Difficile Colitis
A clinical trial, sponsored by Corewell Health East.
- Terminated
- Registry status
- 1
- Enrollment target
NCT01309750 is a clinical trial that was terminated before completion, run by Corewell Health East. The registered enrollment target is 1 participants.
The verdict
NCT01309750 was terminated before completion, sponsored by Corewell Health East.
- TERMINATED
- Registry status
- 1 participants
- Enrollment target
Study Summary
Clostridium difficile is a bacteria that can infect the colon and cause severe diarrhea in patients after recent antibiotic use. The current standard of care treatment for severe C. diff. consists of oral vancomycin and/or intravenous metronidazole. When treatment is unsuccessful, it can lead to need for removal of the entire colon or even death. In fact, mortality rates in the literature range from 11-37% for C. diff. The most commonly quoted mortality rate is 14% for severe infection. It is believed that the failure of treatment may stem from an adynamic ileus (paralysis of the small bowel). This ileus may prevent the oral vancomycin from reaching the colon and therefore it does not treat the problem. Vancomycin functions by direct contact with the colon. It is presumed that this paralysis of the small intestine is present but has never been proven. The objective of the study is to prove that there is an adynamic ileus present in c. diff colitis and therefore lead to investigations into improved treatment.
Interventions
- RADIATION Small Bowel Transit Study
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1 participants |
| Start Date | 2011-04 |
| Est. Completion | 2012-02 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01309750
The ClinicalTrials.gov registry entry for NCT01309750 describes a study currently listed as terminated, categorized as an unspecified phase. The registered enrollment target is 1 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Corewell Health East, which has 106 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Small Bowel Transit Study is the first listed.
NCT01309750 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01309750 about?
NCT01309750 is a clinical study titled "Small Bowel Transit Time in Clostridium Difficile Colitis". Clostridium difficile is a bacteria that can infect the colon and cause severe diarrhea in patients after recent antibiotic use. The current standard of care treatment for severe C. diff. consists of oral vancomycin and/or intravenous metronidazole. When treatment is unsuccessful, it can lead to nee...
What is the current status of trial NCT01309750?
This trial is currently terminated. The enrollment target is 1 participants. The study started on 2011-04. Estimated completion is 2012-02.
What interventions are being tested in trial NCT01309750?
The interventions under investigation include: Small Bowel Transit Study (RADIATION).
Who is sponsoring clinical trial NCT01309750?
This trial is sponsored by Corewell Health East, which has 106 total clinical trials registered on ClinicalTrials.gov.
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