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NCT01301027 · ClinicalTrials.gov registry record · NA

Effect of Adipokines in Hemodialysis Patients

A NA study, sponsored by University of Utah.

Completed
Registry status
NA
Development phase
95
Enrollment target

NCT01301027: Completed NA study, sponsored by University of Utah.

NCT01301027 is a NA study that has completed, run by University of Utah. The registered enrollment target is 95 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01301027, a NA study, has completed, sponsored by University of Utah.

COMPLETED
Registry status
NA
Development phase
95 participants
Enrollment target

Study Summary

This is a double blinded randomized clinical trial of pioglitazone vs. placebo in overweight or obese, diabetic and non-diabetic hemodialysis patients. This study will examine whether pioglitazone modulates adipokine production by adipose tissue in hemodialysis patients and whether these changes result in reduction of inflammation, insulin resistance and oxidative stress and increase in muscle mass. In addition, this study will also examine the associations of adiposity with adipokines and the metabolic milieu in hemodialysis patients to better understand the biology of adipocytes in uremic milieu.

Primary Outcome

The percent difference in HMW-A concentration geometric mean values from baseline to 6 months was calculated for each arm

Interventions

  • DRUG Placebo
  • DRUG Pioglitazone

Trial Details

FieldValue
Enrollment Target 95 participants
Start Date 2008-05
Est. Completion 2015-12
Phase NA
University of Utah

818 total trials

What the finished NCT01301027 record still lists

NCT01301027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01301027 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01301027 about?

NCT01301027 is a clinical study titled "Effect of Adipokines in Hemodialysis Patients". This is a double blinded randomized clinical trial of pioglitazone vs. placebo in overweight or obese, diabetic and non-diabetic hemodialysis patients. This study will examine whether pioglitazone modulates adipokine production by adipose tissue in hemodialysis patients and whether these changes res...

What is the current status of trial NCT01301027?

This trial is currently completed. It is a NA study. The enrollment target is 95 participants. The study started on 2008-05. Estimated completion is 2015-12.

What interventions are being tested in trial NCT01301027?

The interventions under investigation include: Placebo (DRUG), Pioglitazone (DRUG).

Who is sponsoring clinical trial NCT01301027?

This trial is sponsored by University of Utah, which has 818 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01301027's enrollment target sits among peer trials

95 931st of 2000 higher than 1,066 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01301027, the US trial registry maintained by the National Library of Medicine. NCT01301027 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.