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NCT01296594 · ClinicalTrials.gov registry record · NA
Improving Antihypertensive Medication Adherence
A NA study of Substance Abuse and High Blood Pressure, sponsored by UConn Health.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT01296594 is a NA study of Substance Abuse and High Blood Pressure that has completed, run by UConn Health. The registered enrollment target is 30 participants, below the 5,259-participant average among 58 other Substance Abuse trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.
The verdict
NCT01296594, a NA study of Substance Abuse and High Blood Pressure, has completed, sponsored by UConn Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
Poor adherence to antihypertensive medications is associated with morbidity, and data suggest that substance abuse may contribute to poor adherence. Contingency management (CM), an intervention highly efficacious for improving outcomes of substance abusers, shows promise in improving medication adherence in a handful of small trials. CM involves providing tangible reinforcement each time the behavior (medication ingestion) is exhibited. Thus far, studies evaluating CM for increasing medication adherence have utilized MEMS caps, but reinforcement of adherence via MEMS caps is done relatively infrequently and with delay, hindering its efficacy. A widely utilized technology that may be more appropriate for reinforcing medication adherence is cell phones, which can record the process of pill ingestion through video functions. As regular monitoring and feedback is important in the efficacy of CM, patients can be provided with daily messages regarding adherence and CM earnings. In this pilot study, we propose to randomize 40 hypertensive substance abusing patients with suboptimal adherence to antihypertensive medications to one of two 12-week treatment conditions: (1) usual care, or (2) usual care with cell phone monitoring and CM. In the CM condition, patients will carry a cell phone and record and send in time- and date-stamped self videos of medication ingestion. These patients will receive congratulatory messages or reminders about adherence, and they will earn vouchers each time medication ingestion occurs at the appropriate time, along with bonuses for sustained adherence. We hypothesize that the CM condition will improve self report and pill count measurements of medication adherence and that it will result in decreased blood pressure. Results from this study may have widespread implications for the use of cell phones as a novel technology to improve medication adherence.
Conditions Studied
Interventions
- OTHER Usual Care
- BEHAVIORAL Contingency Management
Study Locations (1)
Connecticut
- University of Connecticut Health Center - Farmington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2011-02 |
| Est. Completion | 2012-07 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01296594
The ClinicalTrials.gov registry entry for NCT01296594 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 5,259-participant average among 58 other Substance Abuse trials with a reported enrollment target (99% lower). The listed sponsor is UConn Health, which has 178 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Substance Abuse appearing as the primary indexed condition, and to 2 interventions - of which Usual Care is the first listed.
NCT01296594 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT01296594 about?
NCT01296594 is a clinical study titled "Improving Antihypertensive Medication Adherence". Poor adherence to antihypertensive medications is associated with morbidity, and data suggest that substance abuse may contribute to poor adherence. Contingency management (CM), an intervention highly efficacious for improving outcomes of substance abusers, shows promise in improving medication adhe...
What is the current status of trial NCT01296594?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2011-02. Estimated completion is 2012-07.
What conditions does trial NCT01296594 study?
This clinical trial studies the following conditions: Substance Abuse, High Blood Pressure.
What interventions are being tested in trial NCT01296594?
The interventions under investigation include: Usual Care (OTHER), Contingency Management (BEHAVIORAL).
Who is sponsoring clinical trial NCT01296594?
This trial is sponsored by UConn Health, which has 178 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01296594 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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