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NCT01291888 · ClinicalTrials.gov registry record
Nebivolol Versus Sustained Release Metoprolol Succinate in Patients With Chronic Kidney Disease
A clinical trial, sponsored by University of Michigan.
- Completed
- Registry status
- 50
- Enrollment target
NCT01291888: Completed study, sponsored by University of Michigan.
NCT01291888 is a clinical trial that has completed, run by University of Michigan. The registered enrollment target is 50 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01291888 has completed, sponsored by University of Michigan.
- COMPLETED
- Registry status
- 50 participants
- Enrollment target
Study Summary
The investigators postulate that nebivolol will be more effective than an equivalent dose of a comparative BB, specifically sustained release metoprolol succinate, in improving the availability of NO, lowering blood pressure, and reducing albuminuria with implications for slowing progression of CKD and cardiovascular protection in this high risk population. The objective of this proposal is to conduct a randomized pilot clinical trial to determine the relative efficacy and tolerability of nebivolol versus sustained release metoprolol succinate in improving blood pressure in patients with CKD and albuminuria. The primary endpoint would be a decrease in asymmetric dimethyl arginine (ADMA). Secondary endpoints would include a reduction in blood pressure, urinary F2-isoprostanes and albuminuria.
Primary Outcome
The primary efficacy variable will be the change in ADMA level from baseline to end of study.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2011-03 |
| Est. Completion | 2014-01 |
What the finished NCT01291888 record still lists
NCT01291888 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01291888 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01291888 about?
NCT01291888 is a clinical study titled "Nebivolol Versus Sustained Release Metoprolol Succinate in Patients With Chronic Kidney Disease". The investigators postulate that nebivolol will be more effective than an equivalent dose of a comparative BB, specifically sustained release metoprolol succinate, in improving the availability of NO, lowering blood pressure, and reducing albuminuria with implications for slowing progression of CKD ...
What is the current status of trial NCT01291888?
This trial is currently completed. The enrollment target is 50 participants. The study started on 2011-03. Estimated completion is 2014-01.
Who is sponsoring clinical trial NCT01291888?
This trial is sponsored by University of Michigan, which has 1,327 total clinical trials registered on ClinicalTrials.gov.
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