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NCT01287052 · ClinicalTrials.gov registry record · NA
Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)
A NA study, sponsored by Children's Hospitals and Clinics of Minnesota.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
NCT01287052: Completed NA study, sponsored by Children's Hospitals and Clinics of Minnesota.
NCT01287052 is a NA study that has completed, run by Children's Hospitals and Clinics of Minnesota. The registered enrollment target is 30 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01287052, a NA study, has completed, sponsored by Children's Hospitals and Clinics of Minnesota.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
Study Summary
BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids. Nitrous oxide has analgesic properties similar to those of opioids and is easy to administer. It has been shown in two small studies to be effective in treating migraine headaches. RESEARCH QUESTION Does nitrous oxide act as a safe, less invasive, and effective treatment of acute migraine headaches in children and adolescents presenting to an Emergency Department? DESIGN This is a prospective non-randomized self-controlled study. Repeated measures will be taken to examine change in pain scores before and after nitrous oxide treatment. METHODS Each participant will be given nitrous oxide until he/she reports a pain score of zero or up to fifteen minutes. Study subjects will be asked to rate their pain on a scale of 0-10 before the treatment and after the treatment at multiple time-points.
Interventions
- DRUG Nitrous Oxide
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2011-06 |
| Est. Completion | 2015-01 |
| Phase | NA |
What the finished NCT01287052 record still lists
NCT01287052 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 0 conditions, and to 1 intervention - of which Nitrous Oxide is the first listed.
NCT01287052 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01287052 about?
NCT01287052 is a clinical study titled "Nitrous Oxide for Acute Migraine Pain in the Emergency Room (ED)". BACKGROUND Migraine headaches account for 8-18% of all headaches seen in pediatric emergency rooms. Standard treatment includes IV pain medications, anti-emetics, and IV fluids. Nitrous oxide has analgesic properties similar to those of opioids and is easy to administer. It has been shown in two sma...
What is the current status of trial NCT01287052?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2011-06. Estimated completion is 2015-01.
What interventions are being tested in trial NCT01287052?
The interventions under investigation include: Nitrous Oxide (DRUG).
Who is sponsoring clinical trial NCT01287052?
This trial is sponsored by Children's Hospitals and Clinics of Minnesota, which has 31 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01287052's enrollment target sits among peer trials
30 1593rd of 2000 higher than 299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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