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NCT01280149 · ClinicalTrials.gov registry record · Phase 1
Reduction of IgE Antibody in Human Allergic Subjects
A Phase 1 study, sponsored by Northwestern University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT01280149: Completed Phase 1 study, sponsored by Northwestern University.
NCT01280149 is a Phase 1 study that has completed, run by Northwestern University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01280149, a Phase 1 study, has completed, sponsored by Northwestern University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to determine whether a neuropeptide, substance P, when injected along with an allergen, such as ragweed, can reduce allergic reactivity.
Primary Outcome
The ID50 skin test result utilizes FDA CBER methodology to determine the change in allergic skin reactivity to ragweed and grass pollen allergens.
Interventions
- BIOLOGICAL substance P
- BIOLOGICAL substance P injections
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2011-01 |
| Est. Completion | 2017-06-20 |
| Phase | Phase 1 |
What the finished NCT01280149 record still lists
NCT01280149 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which substance P is the first listed.
NCT01280149 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01280149 about?
NCT01280149 is a clinical study titled "Reduction of IgE Antibody in Human Allergic Subjects". The purpose of this study is to determine whether a neuropeptide, substance P, when injected along with an allergen, such as ragweed, can reduce allergic reactivity.
What is the current status of trial NCT01280149?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2011-01. Estimated completion is 2017-06-20.
What interventions are being tested in trial NCT01280149?
The interventions under investigation include: substance P (BIOLOGICAL), substance P injections (BIOLOGICAL).
Who is sponsoring clinical trial NCT01280149?
This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01280149's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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