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NCT01275235 · ClinicalTrials.gov registry record
Exposure to Type II Diabetes for Two Siblings With the Same Parents
A clinical trial, sponsored by Pennington Biomedical Research Center.
- Terminated
- Registry status
- 10
- Enrollment target
NCT01275235: Clinical Trial study, sponsored by Pennington Biomedical Research Center.
NCT01275235 is a clinical trial that was terminated before completion, run by Pennington Biomedical Research Center. The registered enrollment target is 10 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01275235 was terminated before completion, sponsored by Pennington Biomedical Research Center.
- TERMINATED
- Registry status
- 10 participants
- Enrollment target
Study Summary
Individuals with a family history of type 2 diabetes mellitus (T2DM) are known to be at greater risk for the disease, and studies have shown that how the body responds to insulin, how the muscle creates energy, and the amount of fat stored inside skeletal muscle are often different in these individuals at a young age compared to people without a family history of the disease. The tendency to develop T2DM is influenced strongly by genetics; however, exposure to the surrounding environment may also play a role. The exposure to a diabetic environment while in the womb represents an altered nutritional exposure (high levels of circulating sugar, or glucose) that may affect how tissues important in regulating energy metabolism, such as the pancreas, liver, and skeletal muscle, develop. the purpose of this study is to measure sensitivity to insulin, energy expenditure, fat content of the abdomen and skeletal muscle function in young adult sibling pairs who were raised together but who are discordant for intrauterine exposure to diabetes (i.e., the mother did ot have diabetes during pregnancy with the older sibling, but did have diabetes during pregnancy with the younger sibling).
Primary Outcome
The purpose is to measure sensitivity to insulin, energy expenditure, fat content of the abdomen and skeletal muscle function in young adult sibling pairs who were raised together but who are discordant for intrauterine exposure to diabetes (i.e., the mother did not have diabetes during pregnancy with the older sibling, but did have diabetes during pregnancy with the younger sibling).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2012-12 |
| Est. Completion | 2013-03 |
Why NCT01275235 stopped before completion
NCT01275235 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 10 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01275235 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01275235 about?
NCT01275235 is a clinical study titled "Exposure to Type II Diabetes for Two Siblings With the Same Parents". Individuals with a family history of type 2 diabetes mellitus (T2DM) are known to be at greater risk for the disease, and studies have shown that how the body responds to insulin, how the muscle creates energy, and the amount of fat stored inside skeletal muscle are often different in these individu...
What is the current status of trial NCT01275235?
This trial is currently terminated. The enrollment target is 10 participants. The study started on 2012-12. Estimated completion is 2013-03.
Who is sponsoring clinical trial NCT01275235?
This trial is sponsored by Pennington Biomedical Research Center, which has 258 total clinical trials registered on ClinicalTrials.gov.
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