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NCT01268020 · ClinicalTrials.gov registry record · Early Phase 1

Evaluation of [18F] FMH3 and PET as a Marker of Histamine-3 Receptor Activity in Subjects With AD Compared w/ HC

A Early Phase 1 study, sponsored by Institute for Neurodegenerative Disorders.

Completed
Registry status
Early Phase 1
Development phase
5
Enrollment target

NCT01268020: Completed Early Phase 1 study, sponsored by Institute for Neurodegenerative Disorders.

NCT01268020 is a Early Phase 1 study that has completed, run by Institute for Neurodegenerative Disorders. The registered enrollment target is 5 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01268020, a Early Phase 1 study, has completed, sponsored by Institute for Neurodegenerative Disorders.

COMPLETED
Registry status
Early Phase 1
Development phase
5 participants
Enrollment target

Study Summary

The underlying goal of this study is to assess \[18F\]-FMH3 PET imaging as a tool to evaluate the activity of the H3 receptor in the brain of Alzheimer Disease (AD) research participants

Primary Outcome

To assess the dynamic uptake and washout of \[18F\]-FMH3, an imaging marker targeting the histamine H3 receptor in brain, using positron emission tomography (PET) in subjects with Alzheimer (AD) and healthy controls (HC).

Interventions

  • DRUG [18F]-FMH3

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2010-12
Est. Completion 2012-10
Phase Early Phase 1

What the finished NCT01268020 record still lists

NCT01268020 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (91% lower).

The record links to 0 conditions, and to 1 intervention - of which [18F]-FMH3 is the first listed.

NCT01268020 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01268020 about?

NCT01268020 is a clinical study titled "Evaluation of [18F] FMH3 and PET as a Marker of Histamine-3 Receptor Activity in Subjects With AD Compared w/ HC". The underlying goal of this study is to assess \[18F\]-FMH3 PET imaging as a tool to evaluate the activity of the H3 receptor in the brain of Alzheimer Disease (AD) research participants

What is the current status of trial NCT01268020?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 5 participants. The study started on 2010-12. Estimated completion is 2012-10.

What interventions are being tested in trial NCT01268020?

The interventions under investigation include: [18F]-FMH3 (DRUG).

Who is sponsoring clinical trial NCT01268020?

This trial is sponsored by Institute for Neurodegenerative Disorders, which has 37 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01268020's enrollment target sits among peer trials

5 1888th of 2000 higher than 80 of 2,000 other Early Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01268020, the US trial registry maintained by the National Library of Medicine. NCT01268020 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.