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NCT01257750 · ClinicalTrials.gov registry record · Phase 1

Treatment of Corneal Neovascularization With Topical Pazopanib

A Phase 1 study, sponsored by Reza Dana, MD.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT01257750 is a Phase 1 study that has completed, run by Reza Dana, MD. The registered enrollment target is 20 participants.

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The verdict

NCT01257750, a Phase 1 study, has completed, sponsored by Reza Dana, MD.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

The purpose of this study is to determine the safety and efficacy of a drug \[Pazopanib (Votrient)\] as a treatment for corneal neovascularization. The cornea is the clear, central portion of the eye and neovascularization means blood vessel growth. The cornea is typically avascular, or without blood vessels. Corneal neovascularization in the cornea and can put vision at risk. Numerous diseases of the cornea such as inflammation, ischemia (restriction of blood supply), infection, degeneration (or deterioration), trauma, or corneal stem cell deficiency can lead to corneal neovascularization. This major ocular complication can lead to corneal scarring, edema (swelling), lipid deposits, and inflammation that may significantly alter your vision. In addition, it worsens the outcome of potential future treatments, such as a corneal transplant. A corneal transplant is a treatment that many patients with severe corneal disease may ultimately need.

Interventions

  • DRUG Pazopanib (5mg/ml)

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2010-11
Est. Completion 2012-01
Phase Phase 1

Sponsor

Reza Dana, MD

5 total trials

What the Registry Record Tells You About NCT01257750

The ClinicalTrials.gov registry entry for NCT01257750 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Reza Dana, MD, which has 5 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Pazopanib (5mg/ml) is the first listed.

NCT01257750 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01257750 about?

NCT01257750 is a clinical study titled "Treatment of Corneal Neovascularization With Topical Pazopanib". The purpose of this study is to determine the safety and efficacy of a drug \[Pazopanib (Votrient)\] as a treatment for corneal neovascularization. The cornea is the clear, central portion of the eye and neovascularization means blood vessel growth. The cornea is typically avascular, or without bloo...

What is the current status of trial NCT01257750?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2010-11. Estimated completion is 2012-01.

What interventions are being tested in trial NCT01257750?

The interventions under investigation include: Pazopanib (5mg/ml) (DRUG).

Who is sponsoring clinical trial NCT01257750?

This trial is sponsored by Reza Dana, MD, which has 5 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.