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NCT01245634 · ClinicalTrials.gov registry record · Phase 2
A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery
A Phase 2 study, sponsored by Hoffmann-La Roche.
- Completed
- Registry status
- Phase 2
- Development phase
- 384
- Enrollment target
NCT01245634: Completed Phase 2 study, sponsored by Hoffmann-La Roche.
NCT01245634 is a Phase 2 study that has completed, run by Hoffmann-La Roche. The registered enrollment target is 384 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01245634, a Phase 2 study, has completed, sponsored by Hoffmann-La Roche.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 384 participants
- Enrollment target
Study Summary
This randomized double-blind, placebo-controlled study will evaluate the efficacy and safety of RO4905417 in the prevention of saphenous vein graft disease in patients undergoing elective or urgent coronary artery bypass (CABG) surgery. Patients will be randomized to receive either RO4905417 20 mg/kg by intravenous infusion or placebo every 4 weeks for 32 weeks.
Interventions
- DRUG Placebo
- DRUG RO4905417
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 384 participants |
| Start Date | 2010-12 |
| Est. Completion | 2013-05 |
| Phase | Phase 2 |
What the finished NCT01245634 record still lists
NCT01245634 is an interventional study that assigns participants to a tested intervention. The registered 384 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (189% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01245634 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01245634 about?
NCT01245634 is a clinical study titled "A Study of RO4905417 in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery". This randomized double-blind, placebo-controlled study will evaluate the efficacy and safety of RO4905417 in the prevention of saphenous vein graft disease in patients undergoing elective or urgent coronary artery bypass (CABG) surgery. Patients will be randomized to receive either RO4905417 20 mg/k...
What is the current status of trial NCT01245634?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 384 participants. The study started on 2010-12. Estimated completion is 2013-05.
What interventions are being tested in trial NCT01245634?
The interventions under investigation include: Placebo (DRUG), RO4905417 (DRUG).
Who is sponsoring clinical trial NCT01245634?
This trial is sponsored by Hoffmann-La Roche, which has 909 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01245634's enrollment target sits among peer trials
384 111th of 2000 higher than 1,890 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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