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NCT01244880 · ClinicalTrials.gov registry record · Phase 1
Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects
A Phase 1 study, sponsored by Pfizer.
- Terminated
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT01244880: Clinical Trial Phase 1 study, sponsored by Pfizer.
NCT01244880 is a Phase 1 study that was terminated before completion, run by Pfizer. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01244880, a Phase 1 study, was terminated before completion, sponsored by Pfizer.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
To evaluate whether PF-02545920 reduces the effects of ketamine on brain activation during causal learning as measured by fMRI compared to placebo in healthy human subjects, and to evaluate whether behavioral measures of abnormal causal learning under ketamine are reduced by treatment with PF 02545920.
Interventions
- OTHER Saline
- DRUG PF-02545920
- OTHER Ketamine
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2011-04 |
| Est. Completion | 2012-08 |
| Phase | Phase 1 |
Why NCT01244880 stopped before completion
NCT01244880 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 3 interventions - of which Saline is the first listed.
NCT01244880 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01244880 about?
NCT01244880 is a clinical study titled "Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects". To evaluate whether PF-02545920 reduces the effects of ketamine on brain activation during causal learning as measured by fMRI compared to placebo in healthy human subjects, and to evaluate whether behavioral measures of abnormal causal learning under ketamine are reduced by treatment with PF 025459...
What is the current status of trial NCT01244880?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2011-04. Estimated completion is 2012-08.
What interventions are being tested in trial NCT01244880?
The interventions under investigation include: Saline (OTHER), PF-02545920 (DRUG), Ketamine (OTHER).
Who is sponsoring clinical trial NCT01244880?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01244880's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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