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NCT01242514 · ClinicalTrials.gov registry record · Phase 3

Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)

A Phase 3 study, sponsored by AstraZeneca.

Terminated
Registry status
Phase 3
Development phase
1,917
Enrollment target

NCT01242514: Clinical Trial Phase 3 study, sponsored by AstraZeneca.

NCT01242514 is a Phase 3 study that was terminated before completion, run by AstraZeneca. The registered enrollment target is 1,917 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (148% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01242514, a Phase 3 study, was terminated before completion, sponsored by AstraZeneca.

TERMINATED
Registry status
Phase 3
Development phase
1,917 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the long term safety and tolerability of fostamatinib in patients with rheumatoid arthritis (RA).

Primary Outcome

AE = adverse event, bid = twice daily, IP = investigational product, qd = once daily, SAE = serious adverse event

Interventions

  • DRUG Fostamatinib

Trial Details

FieldValue
Enrollment Target 1,917 participants
Start Date 2011-01
Est. Completion 2015-01
Phase Phase 3
AstraZeneca

1,285 total trials

Why NCT01242514 stopped before completion

NCT01242514 is an interventional study that assigns participants to a tested intervention. Its 1,917 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (148% higher).

The record links to 0 conditions, and to 1 intervention - of which Fostamatinib is the first listed.

NCT01242514 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01242514 about?

NCT01242514 is a clinical study titled "Evaluation of Long-term Safety and Effectiveness of Fostamatinib in the Treatment of Rheumatoid Arthritis (RA)". The purpose of this study is to evaluate the long term safety and tolerability of fostamatinib in patients with rheumatoid arthritis (RA).

What is the current status of trial NCT01242514?

This trial is currently terminated. It is a Phase 3 study. The enrollment target is 1,917 participants. The study started on 2011-01. Estimated completion is 2015-01.

What interventions are being tested in trial NCT01242514?

The interventions under investigation include: Fostamatinib (DRUG).

Who is sponsoring clinical trial NCT01242514?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01242514's enrollment target sits among peer trials

1,917 109th of 2000 higher than 1,892 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01242514, the US trial registry maintained by the National Library of Medicine. NCT01242514 (large enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.