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NCT01241669 · ClinicalTrials.gov registry record · Phase 1

Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity

A Phase 1 study, sponsored by Eisai.

Completed
Registry status
Phase 1
Development phase
104
Enrollment target

NCT01241669 is a Phase 1 study that has completed, run by Eisai. The registered enrollment target is 104 participants.

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The verdict

NCT01241669, a Phase 1 study, has completed, sponsored by Eisai.

COMPLETED
Registry status
Phase 1
Development phase
104 participants
Enrollment target

Study Summary

This is a drug-drug interaction study to evaluate the effects of steady-state exposure of E5555 and its main metabolites on the pharmacokinetics (PK) of metformin, an organic cation transporter-2 (OCT2) substrate. In addition, the study will also investigate the effects of E5555 on several renal function parameters.

Interventions

  • DRUG E5555

Trial Details

FieldValue
Enrollment Target 104 participants
Start Date 2010-10
Phase Phase 1

Sponsor

Eisai

287 total trials

What the Registry Record Tells You About NCT01241669

The ClinicalTrials.gov registry entry for NCT01241669 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 104 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Eisai, which has 287 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which E5555 is the first listed.

NCT01241669 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01241669 about?

NCT01241669 is a clinical study titled "Randomized, Placebo-controlled Study to Evaluate Effects of E5555 on Renal Function Parameters and OCT2 Activity". This is a drug-drug interaction study to evaluate the effects of steady-state exposure of E5555 and its main metabolites on the pharmacokinetics (PK) of metformin, an organic cation transporter-2 (OCT2) substrate. In addition, the study will also investigate the effects of E5555 on several renal fun...

What is the current status of trial NCT01241669?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 104 participants. The study started on 2010-10.

What interventions are being tested in trial NCT01241669?

The interventions under investigation include: E5555 (DRUG).

Who is sponsoring clinical trial NCT01241669?

This trial is sponsored by Eisai, which has 287 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.