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NCT01239901 · ClinicalTrials.gov registry record
Iron Mediated Vascular Disease in Sickle Cell Anemia Patients
A clinical trial, sponsored by Children's Hospital Los Angeles.
- Completed
- Registry status
- 150
- Enrollment target
NCT01239901: Completed study, sponsored by Children's Hospital Los Angeles.
NCT01239901 is a clinical trial that has completed, run by Children's Hospital Los Angeles. The registered enrollment target is 150 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01239901 has completed, sponsored by Children's Hospital Los Angeles.
- COMPLETED
- Registry status
- 150 participants
- Enrollment target
Study Summary
The purpose of this research study is to determine the frequency and severity of iron overload in patients with Sickle Cell Anemia and its relationship to blood vessel function. The investigators hypothesize that intermittent transfusions that these patients receive during hospitalizations produces significant iron overload and impairs blood vessel relaxation.
Primary Outcome
Liver iron concentration (LIC) will be used as a surrogate for total body iron, pancreatic iron represents a surrogate for extravascular iron deposition, and renal iron as a surrogate for chronic intravascular hemolysis. In addition, labile plasma iron will be measured in blood plasma.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2009-12 |
| Est. Completion | 2018-10 |
What the finished NCT01239901 record still lists
NCT01239901 is an observational study that tracks outcomes without assigning an intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT01239901 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01239901 about?
NCT01239901 is a clinical study titled "Iron Mediated Vascular Disease in Sickle Cell Anemia Patients". The purpose of this research study is to determine the frequency and severity of iron overload in patients with Sickle Cell Anemia and its relationship to blood vessel function. The investigators hypothesize that intermittent transfusions that these patients receive during hospitalizations produces ...
What is the current status of trial NCT01239901?
This trial is currently completed. The enrollment target is 150 participants. The study started on 2009-12. Estimated completion is 2018-10.
Who is sponsoring clinical trial NCT01239901?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
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