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NCT01234441 · ClinicalTrials.gov registry record · NA
Intra Hemodialytic Oral Protein and Exercise (IHOPE)
A NA study, sponsored by University of Illinois at Urbana-Champaign.
- Completed
- Registry status
- NA
- Development phase
- 138
- Enrollment target
NCT01234441 is a NA study that has completed, run by University of Illinois at Urbana-Champaign. The registered enrollment target is 138 participants.
The verdict
NCT01234441, a NA study, has completed, sponsored by University of Illinois at Urbana-Champaign.
- COMPLETED
- Registry status
- NA
- Development phase
- 138 participants
- Enrollment target
Study Summary
Chronic kidney disease (CKD) patients receiving hemodialysis treatment (CKD stage 5) suffer from a variety of co-morbid diseases, many of which may be mechanistically linked. Protein malnutrition, muscle catabolism and wasting are especially common, and these lead to reduced muscle strength, declines in physical function, and low levels of physical activity. Physical inactivity exacerbates these functional declines, and also promotes cardiovascular disease (CVD) and bone disorders. This cycle of disease and disability greatly reduces quality of life (QOL) and increases mortality rates in dialysis patients. Many factors contribute to the development of these co-morbidities. Chronic inflammation is believed to be a cause and a consequence of the protein malnutrition, CVD and bone disorders in dialysis patients. In addition, abnormalities in mineral metabolism resulting from the deficit in kidney function promote the loss of mineral from bone and the deposition of mineral in the vasculature, a process termed vascular calcification (VC). VC is associated with a variety of CVD-related disorders, including arterial stiffness, increases in arterial wall intima-media thickness (IMT), left ventricular hypertrophy (LVH), and declines in cardiac function. As a result of these abnormalities, cardiovascular events are 10 to 30 times greater in dialysis patients than in age- and sex-matched subjects in the general population.
Interventions
- DIETARY_SUPPLEMENT Control
- DIETARY_SUPPLEMENT Protein
- BEHAVIORAL Protein + Exercise
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 138 participants |
| Start Date | 2010-12 |
| Est. Completion | 2018-07 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01234441
The ClinicalTrials.gov registry entry for NCT01234441 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 138 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Illinois at Urbana-Champaign, which has 129 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Control is the first listed.
NCT01234441 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01234441 about?
NCT01234441 is a clinical study titled "Intra Hemodialytic Oral Protein and Exercise (IHOPE)". Chronic kidney disease (CKD) patients receiving hemodialysis treatment (CKD stage 5) suffer from a variety of co-morbid diseases, many of which may be mechanistically linked. Protein malnutrition, muscle catabolism and wasting are especially common, and these lead to reduced muscle strength, decline...
What is the current status of trial NCT01234441?
This trial is currently completed. It is a NA study. The enrollment target is 138 participants. The study started on 2010-12. Estimated completion is 2018-07.
What interventions are being tested in trial NCT01234441?
The interventions under investigation include: Control (DIETARY_SUPPLEMENT), Protein (DIETARY_SUPPLEMENT), Protein + Exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT01234441?
This trial is sponsored by University of Illinois at Urbana-Champaign, which has 129 total clinical trials registered on ClinicalTrials.gov.
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