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NCT01233869 · ClinicalTrials.gov registry record · Phase 2
Bosutinib For Autosomal Dominant Polycystic Kidney Disease
A Phase 2 study, sponsored by Pfizer.
- Completed
- Registry status
- Phase 2
- Development phase
- 172
- Enrollment target
NCT01233869: Completed Phase 2 study, sponsored by Pfizer.
NCT01233869 is a Phase 2 study that has completed, run by Pfizer. The registered enrollment target is 172 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01233869, a Phase 2 study, has completed, sponsored by Pfizer.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 172 participants
- Enrollment target
Study Summary
This purpose of this study is to determine if bosutinib reduces the rate of kidney enlargement in subjects with autosomal dominant polycystic kidney disease (ADPKD) entering the study with a total kidney volume greater than or equal to 750 cc and eGFR greater than or equal to 60 mL/min/1.73m2.
Primary Outcome
TKV was measured by centrally evaluated Magnetic Resonance Imaging (MRI).
Interventions
- DRUG Placebo
- DRUG Bosutinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 172 participants |
| Start Date | 2010-12 |
| Est. Completion | 2014-08 |
| Phase | Phase 2 |
What the finished NCT01233869 record still lists
NCT01233869 is an interventional study that assigns participants to a tested intervention. The registered 172 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (29% higher).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01233869 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01233869 about?
NCT01233869 is a clinical study titled "Bosutinib For Autosomal Dominant Polycystic Kidney Disease". This purpose of this study is to determine if bosutinib reduces the rate of kidney enlargement in subjects with autosomal dominant polycystic kidney disease (ADPKD) entering the study with a total kidney volume greater than or equal to 750 cc and eGFR greater than or equal to 60 mL/min/1.73m2.
What is the current status of trial NCT01233869?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 172 participants. The study started on 2010-12. Estimated completion is 2014-08.
What interventions are being tested in trial NCT01233869?
The interventions under investigation include: Placebo (DRUG), Bosutinib (DRUG).
Who is sponsoring clinical trial NCT01233869?
This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01233869's enrollment target sits among peer trials
172 397th of 2000 higher than 1,603 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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