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NCT01227343 · ClinicalTrials.gov registry record
Nicotine and Brain Imaging Research Study
A clinical trial, sponsored by University of Pennsylvania.
- Completed
- Registry status
- 54
- Enrollment target
NCT01227343: Completed study, sponsored by University of Pennsylvania.
NCT01227343 is a clinical trial that has completed, run by University of Pennsylvania. The registered enrollment target is 54 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01227343 has completed, sponsored by University of Pennsylvania.
- COMPLETED
- Registry status
- 54 participants
- Enrollment target
Study Summary
The aim of this study is to assess the impact of smoking on cortical GABA levels in males and females. Using magnetic resonance spectroscopy (MRS), we will examine the impact of sex and menstrual cycle phase on brain neurochemistry in healthy smokers and non-smokers. We hypothesize that female, but not male, smokers will have reduced cortical GABA levels compared to their non-smoking, sex-matched counterparts.
Primary Outcome
Preliminary findings suggest that nicotine's effects on cortical GABA levels vary by sex with women experiencing the greatest smoking-induced alterations in cortical GABA levels. We hypothesize that female, but not male, smokers will have reduced cortical GABA levels compared to their non-smoking, sex-matched counterparts.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 54 participants |
| Start Date | 2010-03 |
| Est. Completion | 2017-11 |
What the finished NCT01227343 record still lists
NCT01227343 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 54 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT01227343 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01227343 about?
NCT01227343 is a clinical study titled "Nicotine and Brain Imaging Research Study". The aim of this study is to assess the impact of smoking on cortical GABA levels in males and females. Using magnetic resonance spectroscopy (MRS), we will examine the impact of sex and menstrual cycle phase on brain neurochemistry in healthy smokers and non-smokers. We hypothesize that female, but ...
What is the current status of trial NCT01227343?
This trial is currently completed. The enrollment target is 54 participants. The study started on 2010-03. Estimated completion is 2017-11.
Who is sponsoring clinical trial NCT01227343?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
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