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NCT01222195 · ClinicalTrials.gov registry record · Phase 2

Lenalidomide and Darbepoetin in Low-Intermediate Risk Myelodysplastic Syndrome (MDS)

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
1
Enrollment target

NCT01222195: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT01222195 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 1 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01222195, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
1 participants
Enrollment target

Study Summary

The goal of this clinical research study is to learn if lenalidomide and darbepoetin alfa given together will help to control the need for transfusions in patients with low to intermediate risk Myelodysplastic Syndrome (MDS). The safety of this combination will also be studied.

Primary Outcome

Response defined as transfusion independence (no red blood cell transfusions) for at least 8 weeks, anytime during the six 28-day cycles of therapy.

Interventions

  • DRUG Lenalidomide
  • DRUG Darbepoetin alfa

Trial Details

FieldValue
Enrollment Target 1 participants
Start Date 2008-02
Est. Completion 2010-07
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

Why NCT01222195 stopped before completion

NCT01222195 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 1 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Lenalidomide is the first listed.

NCT01222195 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01222195 about?

NCT01222195 is a clinical study titled "Lenalidomide and Darbepoetin in Low-Intermediate Risk Myelodysplastic Syndrome (MDS)". The goal of this clinical research study is to learn if lenalidomide and darbepoetin alfa given together will help to control the need for transfusions in patients with low to intermediate risk Myelodysplastic Syndrome (MDS). The safety of this combination will also be studied.

What is the current status of trial NCT01222195?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 1 participants. The study started on 2008-02. Estimated completion is 2010-07.

What interventions are being tested in trial NCT01222195?

The interventions under investigation include: Lenalidomide (DRUG), Darbepoetin alfa (DRUG).

Who is sponsoring clinical trial NCT01222195?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01222195's enrollment target sits among peer trials

1 2001st of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01222195, the US trial registry maintained by the National Library of Medicine. NCT01222195 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.