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NCT01219738 · ClinicalTrials.gov registry record · NA
Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
A NA study, sponsored by University of Miami.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT01219738 is a NA study that has completed, run by University of Miami. The registered enrollment target is 20 participants.
The verdict
NCT01219738, a NA study, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation. One of these non-genomic effects is the inhibition of adrenergic agonist transport into airway vascular smooth muscle cells with an increase of adrenergic agonist concentrations at adrenergic receptor sites and enhance the physiological effects of endogenous adrenergic agonists (e.g. locally released norepinephrine from noradrenergic neurons) or exogenous adrenergic agonists (e.g. inhaled beta-adrenergic agonists).
Interventions
- DRUG Placebo
- DRUG Budesonide 360ug
- DRUG Budesonide 720ug
- DRUG Budesonide 1440ug
- DRUG Budesonide720ug 4 times
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2008-07 |
| Est. Completion | 2012-08 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01219738
The ClinicalTrials.gov registry entry for NCT01219738 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT01219738 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01219738 about?
NCT01219738 is a clinical study titled "Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide". Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation. One of these non-genomic effects is the inhibition of adrenergic agonist transport into airway vascular smooth muscle cells with an incre...
What is the current status of trial NCT01219738?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2008-07. Estimated completion is 2012-08.
What interventions are being tested in trial NCT01219738?
The interventions under investigation include: Placebo (DRUG), Budesonide 360ug (DRUG), Budesonide 720ug (DRUG), Budesonide 1440ug (DRUG), Budesonide720ug 4 times (DRUG).
Who is sponsoring clinical trial NCT01219738?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
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