Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01219738 · ClinicalTrials.gov registry record · NA
Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide
A NA study, sponsored by University of Miami.
- Completed
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT01219738: Completed NA study, sponsored by University of Miami.
NCT01219738 is a NA study that has completed, run by University of Miami. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01219738, a NA study, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation. One of these non-genomic effects is the inhibition of adrenergic agonist transport into airway vascular smooth muscle cells with an increase of adrenergic agonist concentrations at adrenergic receptor sites and enhance the physiological effects of endogenous adrenergic agonists (e.g. locally released norepinephrine from noradrenergic neurons) or exogenous adrenergic agonists (e.g. inhaled beta-adrenergic agonists).
Primary Outcome
Qaw will be measured before and up to 6 hours after a single inhaled dose of 360ug, 720ug, and 1440ug budesonide or placebo from a DPI, using a double-blinded randomized design on different days.
Interventions
- DRUG Placebo
- DRUG Budesonide 360ug
- DRUG Budesonide 720ug
- DRUG Budesonide 1440ug
- DRUG Budesonide720ug 4 times
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2008-07 |
| Est. Completion | 2012-08 |
| Phase | NA |
What the finished NCT01219738 record still lists
NCT01219738 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 5 interventions - of which Placebo is the first listed.
NCT01219738 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01219738 about?
NCT01219738 is a clinical study titled "Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide". Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation. One of these non-genomic effects is the inhibition of adrenergic agonist transport into airway vascular smooth muscle cells with an incre...
What is the current status of trial NCT01219738?
This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2008-07. Estimated completion is 2012-08.
What interventions are being tested in trial NCT01219738?
The interventions under investigation include: Placebo (DRUG), Budesonide 360ug (DRUG), Budesonide 720ug (DRUG), Budesonide 1440ug (DRUG), Budesonide720ug 4 times (DRUG).
Who is sponsoring clinical trial NCT01219738?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01219738's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT00573339 · 20 participants
Cardiac Magnetic Resonance Imaging (MRI) Normal Reference Control Group Testing
- NCT00692939 · 20 participants · Phase 1
Autologous Stem Cell Transplantation for Crohn's Disease
- NCT00967785 · 20 participants · Phase 1
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
- NCT01406691 · 20 participants · Phase 4
Light Flashes to Treat Delayed Sleep Phase Disorder (DSPD)
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia