Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01217060 · ClinicalTrials.gov registry record · Phase 1
Trimodality Management of T1b Esophageal Cancers
A Phase 1 study, sponsored by M.D. Anderson Cancer Center.
- Completed
- Registry status
- Phase 1
- Development phase
- 4
- Enrollment target
NCT01217060: Completed Phase 1 study, sponsored by M.D. Anderson Cancer Center.
NCT01217060 is a Phase 1 study that has completed, run by M.D. Anderson Cancer Center. The registered enrollment target is 4 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01217060, a Phase 1 study, has completed, sponsored by M.D. Anderson Cancer Center.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 4 participants
- Enrollment target
Study Summary
The goal of this clinical research study is to learn if giving chemotherapy and radiation therapy before surgery for early-stage esophageal cancer can help to control the disease and if so, for how long. The safety of this treatment will also be studied.
Primary Outcome
The primary endpoint for this protocol is to assess the efficacy (pathologic complete response) and safety of Trimodality management (chemoradiotherapy followed by esophagectomy) in patients with clinically staged T1bN0M0 cancer of the esophagus or gastroesophageal junction. This is a single-arm phase IIB trial of chemo-radiation followed by surgery for patients with early stage grade T1b esophageal cancer. The rates of pathologic CR will be tabulated and their possible relationships to baseline
Interventions
- DRUG Docetaxel
- RADIATION Radiotherapy
- DRUG Dexamethasone
- PROCEDURE Esophagectomy
- DRUG 5-FU
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2010-10 |
| Est. Completion | 2020-06-14 |
| Phase | Phase 1 |
What the finished NCT01217060 record still lists
NCT01217060 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (93% lower).
The record links to 0 conditions, and to 5 interventions - of which Docetaxel is the first listed.
NCT01217060 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01217060 about?
NCT01217060 is a clinical study titled "Trimodality Management of T1b Esophageal Cancers". The goal of this clinical research study is to learn if giving chemotherapy and radiation therapy before surgery for early-stage esophageal cancer can help to control the disease and if so, for how long. The safety of this treatment will also be studied.
What is the current status of trial NCT01217060?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 4 participants. The study started on 2010-10. Estimated completion is 2020-06-14.
What interventions are being tested in trial NCT01217060?
The interventions under investigation include: Docetaxel (DRUG), Radiotherapy (RADIATION), Dexamethasone (DRUG), Esophagectomy (PROCEDURE), 5-FU (DRUG).
Who is sponsoring clinical trial NCT01217060?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01217060's enrollment target sits among peer trials
4 1995th of 2000 higher than 2 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia