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NCT01216748 · ClinicalTrials.gov registry record · NA

Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the Airway

A NA study, sponsored by University of Miami.

Completed
Registry status
NA
Development phase
10
Enrollment target

NCT01216748: Completed NA study, sponsored by University of Miami.

NCT01216748 is a NA study that has completed, run by University of Miami. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01216748, a NA study, has completed, sponsored by University of Miami.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

The purpose of this study was to determine if airway pH has an effect on albuterol-induced vasodilation in the airway. Methods: Ten healthy volunteers performed the following respiratory maneuvers: quiet breathing, hypocapnic hyperventilation, hypercapnic hyperventilation, and eucapnic hyperventilation

Primary Outcome

Effect of airway pH on albuterol responsiveness as reflected by the change in airway blood flow after 180μg albuterol by inhalation (ΔQaw) vs baseline.

Interventions

  • OTHER quiet breathing
  • OTHER Hypocapnic Hyperventilation
  • OTHER Hypercapnic Hyperventilation
  • OTHER eucapnic hyperventilation

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2010-01
Est. Completion 2010-08
Phase NA
University of Miami

721 total trials

What the finished NCT01216748 record still lists

NCT01216748 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 4 interventions - of which quiet breathing is the first listed.

NCT01216748 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01216748 about?

NCT01216748 is a clinical study titled "Clinical Evidence of pH Dependent ß2 Adrenergic Transport Mechanisms in the Airway". The purpose of this study was to determine if airway pH has an effect on albuterol-induced vasodilation in the airway. Methods: Ten healthy volunteers performed the following respiratory maneuvers: quiet breathing, hypocapnic hyperventilation, hypercapnic hyperventilation, and eucapnic hyperventilat...

What is the current status of trial NCT01216748?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2010-01. Estimated completion is 2010-08.

What interventions are being tested in trial NCT01216748?

The interventions under investigation include: quiet breathing (OTHER), Hypocapnic Hyperventilation (OTHER), Hypercapnic Hyperventilation (OTHER), eucapnic hyperventilation (OTHER).

Who is sponsoring clinical trial NCT01216748?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01216748's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01216748, the US trial registry maintained by the National Library of Medicine. NCT01216748 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.