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NCT01216735 · ClinicalTrials.gov registry record · NA
Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers
A NA study of Tobacco Abuse Smoke, sponsored by University of Miami.
- Completed
- Registry status
- NA
- Development phase
- 32
- Enrollment target
- 1
- Study location
NCT01216735: Completed NA study of Tobacco Abuse Smoke, sponsored by University of Miami.
NCT01216735 is a NA study of Tobacco Abuse Smoke that has completed, run by University of Miami. The registered enrollment target is 32 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01216735, a NA study of Tobacco Abuse Smoke, has completed, sponsored by University of Miami.
- COMPLETED
- Registry status
- NA
- Development phase
- 32 participants
- Enrollment target
- 1
- Study location
Study Summary
The hypothesis underlying the proposed study is that the blunted endothelium-dependent vasodilation seen in the airway of current smokers is also present in the brachial artery, and that the same inhaled corticosteroid (ICS) treatment regime that reversed endothelial function in the airway of current smokers will also restore endothelium-dependent relaxation in the brachial artery. Non-smokers will be used as controls and will not receive any intervention or treatment.
Primary Outcome
Airway Blood flow (Qaw) will be measured before and 15 minutes after albuterol inhalation (delta Qaw).
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Fluticasone
Study Locations (1)
Florida
- Human Research Laboratory - University of Miami - Miami
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2008-09 |
| Est. Completion | 2010-09 |
| Phase | NA |
What the finished NCT01216735 record still lists
NCT01216735 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Tobacco Abuse Smoke appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT01216735 reports a single indexed study location in Florida.
Frequently Asked Questions
What is clinical trial NCT01216735 about?
NCT01216735 is a clinical study titled "Effect of an Inhaled Glucocorticosteroid (ICS) on Endothelial Dysfunction in Cigarette Smokers". The hypothesis underlying the proposed study is that the blunted endothelium-dependent vasodilation seen in the airway of current smokers is also present in the brachial artery, and that the same inhaled corticosteroid (ICS) treatment regime that reversed endothelial function in the airway of curren...
What is the current status of trial NCT01216735?
This trial is currently completed. It is a NA study. The enrollment target is 32 participants. The study started on 2008-09. Estimated completion is 2010-09.
What conditions does trial NCT01216735 study?
This clinical trial studies the following conditions: Tobacco Abuse Smoke.
What interventions are being tested in trial NCT01216735?
The interventions under investigation include: Placebo (DRUG), Fluticasone (DRUG).
Who is sponsoring clinical trial NCT01216735?
This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01216735 being conducted?
This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01216735's enrollment target sits among peer trials
32 1578th of 2000 higher than 409 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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