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NCT01215799 · ClinicalTrials.gov registry record · Phase 2

Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate Cancer

A Phase 2 study, sponsored by CytRx.

Completed
Registry status
Phase 2
Development phase
23
Enrollment target

NCT01215799: Completed Phase 2 study, sponsored by CytRx.

NCT01215799 is a Phase 2 study that has completed, run by CytRx. The registered enrollment target is 23 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01215799, a Phase 2 study, has completed, sponsored by CytRx.

COMPLETED
Registry status
Phase 2
Development phase
23 participants
Enrollment target

Study Summary

This is a Phase II open-label study evaluating the preliminary efficacy and safety of bafetinib administered as 240 mg orally twice daily in subjects with Hormone Refractory Prostate Cancer.

Primary Outcome

The primary objective of this study is to determine the preliminary efficacy of administration of bafetinib in subjects with hormone-refractory prostate cancer (HRPC), as measured by the objective response rate (ORR), which is a combination of CR (PSA ≤0.12 ng/mL) and PR (≥50% reduction in PSA from baseline).

Interventions

  • DRUG Bafetinib

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2010-08
Est. Completion 2011-12
Phase Phase 2
CytRx

6 total trials

What the finished NCT01215799 record still lists

NCT01215799 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (83% lower).

The record links to 0 conditions, and to 1 intervention - of which Bafetinib is the first listed.

NCT01215799 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01215799 about?

NCT01215799 is a clinical study titled "Study of Bafetinib (INNO-406) as Treatment for Patients With Hormone-Refractory Prostate Cancer". This is a Phase II open-label study evaluating the preliminary efficacy and safety of bafetinib administered as 240 mg orally twice daily in subjects with Hormone Refractory Prostate Cancer.

What is the current status of trial NCT01215799?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 23 participants. The study started on 2010-08. Estimated completion is 2011-12.

What interventions are being tested in trial NCT01215799?

The interventions under investigation include: Bafetinib (DRUG).

Who is sponsoring clinical trial NCT01215799?

This trial is sponsored by CytRx, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01215799's enrollment target sits among peer trials

23 1784th of 2000 higher than 211 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01215799, the US trial registry maintained by the National Library of Medicine. NCT01215799 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.