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NCT01213524 · ClinicalTrials.gov registry record · Phase 2
Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia
A Phase 2 study, sponsored by Brown University.
- Completed
- Registry status
- Phase 2
- Development phase
- 75
- Enrollment target
NCT01213524: Completed Phase 2 study, sponsored by Brown University.
NCT01213524 is a Phase 2 study that has completed, run by Brown University. The registered enrollment target is 75 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01213524, a Phase 2 study, has completed, sponsored by Brown University.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 75 participants
- Enrollment target
Study Summary
The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related negative affect, psychiatric symptoms, cognitive task performance and 90-min ad libitum usual-brand smoking behavior in smokers with schizophrenia and non-psychiatric smokers.
Primary Outcome
preferred brand smoke intake (breath CO) after 5-hr "satiation" periods in which nicotine replacement and sensorimotor replacement were provided under double-blind conditions
Interventions
- BEHAVIORAL sensorimotor replacement
- DRUG 42 mg transdermal nicotine replacement
- DRUG Placebo transdermal nicotine
- OTHER usual brand smoking
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2005-09 |
| Est. Completion | 2011-03 |
| Phase | Phase 2 |
What the finished NCT01213524 record still lists
NCT01213524 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (44% lower).
The record links to 0 conditions, and to 4 interventions - of which sensorimotor replacement is the first listed.
NCT01213524 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01213524 about?
NCT01213524 is a clinical study titled "Nicotine and Sensorimotor Replacement for Smoking in Smokers With Schizophrenia". The objective of this study is to investigate the relative contributions of nicotine replacement and sensorimotor replacement (i.e., smoking denicotinized cigarettes) on abstinence-induced smoking urges, withdrawal-related negative affect, psychiatric symptoms, cognitive task performance and 90-min ...
What is the current status of trial NCT01213524?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 75 participants. The study started on 2005-09. Estimated completion is 2011-03.
What interventions are being tested in trial NCT01213524?
The interventions under investigation include: sensorimotor replacement (BEHAVIORAL), 42 mg transdermal nicotine replacement (DRUG), Placebo transdermal nicotine (DRUG), usual brand smoking (OTHER).
Who is sponsoring clinical trial NCT01213524?
This trial is sponsored by Brown University, which has 231 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01213524's enrollment target sits among peer trials
75 900th of 2000 higher than 1,081 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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