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NCT01210430 · ClinicalTrials.gov registry record · Early Phase 1
Local Vasoconstriction in Postural Tachycardia Syndrome
A Early Phase 1 study, sponsored by New York Medical College.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 74
- Enrollment target
NCT01210430: Completed Early Phase 1 study, sponsored by New York Medical College.
NCT01210430 is a Early Phase 1 study that has completed, run by New York Medical College. The registered enrollment target is 74 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (40% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01210430, a Early Phase 1 study, has completed, sponsored by New York Medical College.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 74 participants
- Enrollment target
Study Summary
The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of POTS in individual patients. Specific causes for POTS may vary from patient to patient. Patients will be compared to healthy control subjects. There is a treatment arm with a medication (losartan) that reduces the binding of angiotensin and increases NO. If the investigators know the specific biochemical mechanism the investigators may be able to offer further specific treatments to specific patients.
Interventions
- DRUG Losartan
- DRUG Normal Saline
- DRUG Ascorbic Acid (Vitamin C)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 74 participants |
| Start Date | 2010-07 |
| Est. Completion | 2015-06 |
| Phase | Early Phase 1 |
What the finished NCT01210430 record still lists
NCT01210430 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 74 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (40% higher).
The record links to 0 conditions, and to 3 interventions - of which Losartan is the first listed.
NCT01210430 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01210430 about?
NCT01210430 is a clinical study titled "Local Vasoconstriction in Postural Tachycardia Syndrome". The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of POTS in individual patients. Specific causes for POTS may vary from pa...
What is the current status of trial NCT01210430?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 74 participants. The study started on 2010-07. Estimated completion is 2015-06.
What interventions are being tested in trial NCT01210430?
The interventions under investigation include: Losartan (DRUG), Normal Saline (DRUG), Ascorbic Acid (Vitamin C) (DRUG).
Who is sponsoring clinical trial NCT01210430?
This trial is sponsored by New York Medical College, which has 47 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01210430's enrollment target sits among peer trials
74 312th of 2000 higher than 1,685 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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