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NCT01210430 · ClinicalTrials.gov registry record · Early Phase 1

Local Vasoconstriction in Postural Tachycardia Syndrome

A Early Phase 1 study, sponsored by New York Medical College.

Completed
Registry status
Early Phase 1
Development phase
74
Enrollment target

NCT01210430 is a Early Phase 1 study that has completed, run by New York Medical College. The registered enrollment target is 74 participants.

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The verdict

NCT01210430, a Early Phase 1 study, has completed, sponsored by New York Medical College.

COMPLETED
Registry status
Early Phase 1
Development phase
74 participants
Enrollment target

Study Summary

The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of POTS in individual patients. Specific causes for POTS may vary from patient to patient. Patients will be compared to healthy control subjects. There is a treatment arm with a medication (losartan) that reduces the binding of angiotensin and increases NO. If the investigators know the specific biochemical mechanism the investigators may be able to offer further specific treatments to specific patients.

Interventions

  • DRUG Losartan
  • DRUG Normal Saline
  • DRUG Ascorbic Acid (Vitamin C)

Trial Details

FieldValue
Enrollment Target 74 participants
Start Date 2010-07
Est. Completion 2015-06
Phase Early Phase 1

Sponsor

New York Medical College

47 total trials

What the Registry Record Tells You About NCT01210430

The ClinicalTrials.gov registry entry for NCT01210430 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 74 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is New York Medical College, which has 47 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Losartan is the first listed.

NCT01210430 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01210430 about?

NCT01210430 is a clinical study titled "Local Vasoconstriction in Postural Tachycardia Syndrome". The investigators study will determine how often blood flow regulation abnormalities and abnormalities of sympathetic regulation produced by nitric oxide, angiotensin-II, and oxidative stress occur in POTS and the mechanism(s) of POTS in individual patients. Specific causes for POTS may vary from pa...

What is the current status of trial NCT01210430?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 74 participants. The study started on 2010-07. Estimated completion is 2015-06.

What interventions are being tested in trial NCT01210430?

The interventions under investigation include: Losartan (DRUG), Normal Saline (DRUG), Ascorbic Acid (Vitamin C) (DRUG).

Who is sponsoring clinical trial NCT01210430?

This trial is sponsored by New York Medical College, which has 47 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.