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NCT01209520 · ClinicalTrials.gov registry record · NA

Residual Hypermethylation in Early Stage Non-Small Cell Lung Cancer (NSCLC) As Part of Adjuvant Therapy and Preventive Strategy

A NA study, sponsored by University of Miami.

Completed
Registry status
NA
Development phase
6
Enrollment target

NCT01209520 is a NA study that has completed, run by University of Miami. The registered enrollment target is 6 participants.

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The verdict

NCT01209520, a NA study, has completed, sponsored by University of Miami.

COMPLETED
Registry status
NA
Development phase
6 participants
Enrollment target

Study Summary

The trial investigates the feasibility and efficacy of targeting Non-Small Cell Lung Cancer (NSCLC) "driven" by epigenetic changes. The investigators study the impact of 5-azacitidine (Vidaza®, Celgene, Summit, NJ, USA) in combination with conventional cytotoxic chemotherapy in a sequential fashion. The study population consists of all NSCLC patients who undergo "curative" lung cancer resection and whose tumors harbor hypermethylation in any of the protocol-specific genes (samples will be banked for additional molecular testing including other 21 loci which have shown to be important in lung carcinogenesis.

Interventions

  • DRUG Carboplatin
  • DRUG Cisplatin
  • DRUG Paclitaxel
  • DRUG Vidaza
  • PROCEDURE Tumor Specimen for Methylation Analysis

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2009-07
Phase NA

Sponsor

University of Miami

721 total trials

What the Registry Record Tells You About NCT01209520

The ClinicalTrials.gov registry entry for NCT01209520 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 6 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Miami, which has 721 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Carboplatin is the first listed.

NCT01209520 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01209520 about?

NCT01209520 is a clinical study titled "Residual Hypermethylation in Early Stage Non-Small Cell Lung Cancer (NSCLC) As Part of Adjuvant Therapy and Preventive Strategy". The trial investigates the feasibility and efficacy of targeting Non-Small Cell Lung Cancer (NSCLC) "driven" by epigenetic changes. The investigators study the impact of 5-azacitidine (Vidaza®, Celgene, Summit, NJ, USA) in combination with conventional cytotoxic chemotherapy in a sequential fashion....

What is the current status of trial NCT01209520?

This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2009-07.

What interventions are being tested in trial NCT01209520?

The interventions under investigation include: Carboplatin (DRUG), Cisplatin (DRUG), Paclitaxel (DRUG), Vidaza (DRUG), Tumor Specimen for Methylation Analysis (PROCEDURE).

Who is sponsoring clinical trial NCT01209520?

This trial is sponsored by University of Miami, which has 721 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.