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NCT01204788 · ClinicalTrials.gov registry record · Phase 2

Prophylactic White Cell Transfusions Versus Therapeutic White Cell Transfusions in Patients With Leukemia

A Phase 2 study, sponsored by M.D. Anderson Cancer Center.

Terminated
Registry status
Phase 2
Development phase
5
Enrollment target

NCT01204788: Clinical Trial Phase 2 study, sponsored by M.D. Anderson Cancer Center.

NCT01204788 is a Phase 2 study that was terminated before completion, run by M.D. Anderson Cancer Center. The registered enrollment target is 5 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01204788, a Phase 2 study, was terminated before completion, sponsored by M.D. Anderson Cancer Center.

TERMINATED
Registry status
Phase 2
Development phase
5 participants
Enrollment target

Study Summary

Patients with leukemia often have low white blood cell counts after chemotherapy, which puts them at greater risk for infection. The standard of care for preventing infections is to give these patients antibiotic, antifungal, and antiviral drugs during the time that white blood cell counts are low. However, many patients still develop infections during chemotherapy. Radiated white blood cell transfusions are a standard treatment once a patient develops a severe infection. The goal of this clinical research study is to learn if giving unirradiated white blood cell transfusions early in chemotherapy might delay or prevent infections in patients with leukemia. Researchers also want to learn more about the type and severity of any infections that do occur.

Primary Outcome

Primary outcome is infection (yes/no) where participant without infection found by day 42 patient are counted as 'No' to infection.

Interventions

  • PROCEDURE Prophylactic White Cell Transfusion
  • PROCEDURE Therapeutic White Cell Transfusion

Trial Details

FieldValue
Enrollment Target 5 participants
Start Date 2010-09
Est. Completion 2013-01
Phase Phase 2
M.D. Anderson Cancer Center

2,692 total trials

Why NCT01204788 stopped before completion

NCT01204788 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (96% lower).

The record links to 0 conditions, and to 2 interventions - of which Prophylactic White Cell Transfusion is the first listed.

NCT01204788 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01204788 about?

NCT01204788 is a clinical study titled "Prophylactic White Cell Transfusions Versus Therapeutic White Cell Transfusions in Patients With Leukemia". Patients with leukemia often have low white blood cell counts after chemotherapy, which puts them at greater risk for infection. The standard of care for preventing infections is to give these patients antibiotic, antifungal, and antiviral drugs during the time that white blood cell counts are low. ...

What is the current status of trial NCT01204788?

This trial is currently terminated. It is a Phase 2 study. The enrollment target is 5 participants. The study started on 2010-09. Estimated completion is 2013-01.

What interventions are being tested in trial NCT01204788?

The interventions under investigation include: Prophylactic White Cell Transfusion (PROCEDURE), Therapeutic White Cell Transfusion (PROCEDURE).

Who is sponsoring clinical trial NCT01204788?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01204788's enrollment target sits among peer trials

5 2000th of 2000 the lowest of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01204788, the US trial registry maintained by the National Library of Medicine. NCT01204788 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.