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NCT01202747 · ClinicalTrials.gov registry record · Phase 2
Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction
A Phase 2 study, sponsored by TearScience.
- Completed
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT01202747: Completed Phase 2 study, sponsored by TearScience.
NCT01202747 is a Phase 2 study that has completed, run by TearScience. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01202747, a Phase 2 study, has completed, sponsored by TearScience.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
The objective is to evaluate the feasibility of using additional screening methods to optimize effectiveness outcomes with the LipiFlow System for application of heat and pressure therapy in adult patients with chronic cystic conditions of the eyelids, including meibomian gland dysfunction, also known as evaporative dry eye or lipid deficiency dry eye, and chalazia. The screening methods include diagnostic expression of the meibomian glands and interferometry assessment of the tear film.
Primary Outcome
Analysis of association between Baseline Meibomian Gland Expression Score and Total Meibomian Gland Score at 4 Weeks. Success was defined by demonstration of a statistically significant (p\<0.05) association between the screening method and outcome. Meibomian gland expression sum scores range from 0 to 60 with a higher score reflecting less meibomian gland dysfunction. Total meibomian gland scores range from 0 to 45 with a higher score reflecting less meibomian gland dysfunction.
Interventions
- DEVICE LipiFlow System
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2010-09 |
| Est. Completion | 2011-01 |
| Phase | Phase 2 |
What the finished NCT01202747 record still lists
NCT01202747 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 1 intervention - of which LipiFlow System is the first listed.
NCT01202747 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01202747 about?
NCT01202747 is a clinical study titled "Evaluation of Screening Methods for Treatment of Meibomian Gland Dysfunction". The objective is to evaluate the feasibility of using additional screening methods to optimize effectiveness outcomes with the LipiFlow System for application of heat and pressure therapy in adult patients with chronic cystic conditions of the eyelids, including meibomian gland dysfunction, also kno...
What is the current status of trial NCT01202747?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2010-09. Estimated completion is 2011-01.
What interventions are being tested in trial NCT01202747?
The interventions under investigation include: LipiFlow System (DEVICE).
Who is sponsoring clinical trial NCT01202747?
This trial is sponsored by TearScience, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01202747's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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