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NCT01189227 · ClinicalTrials.gov registry record · Phase 3
Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery
A Phase 3 study, sponsored by NSABP Foundation.
- Terminated
- Registry status
- Phase 3
- Development phase
- 9
- Enrollment target
NCT01189227: Clinical Trial Phase 3 study, sponsored by NSABP Foundation.
NCT01189227 is a Phase 3 study that was terminated before completion, run by NSABP Foundation. The registered enrollment target is 9 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01189227, a Phase 3 study, was terminated before completion, sponsored by NSABP Foundation.
- TERMINATED
- Registry status
- Phase 3
- Development phase
- 9 participants
- Enrollment target
Study Summary
RATIONALE: Drugs used in chemotherapy work in different ways to kill tumor cells or stop them from growing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving combination chemotherapy after surgery may kill any remaining tumor cells. It is not yet known whether giving combination chemotherapy before and after surgery is more effective than giving combination chemotherapy after surgery. PURPOSE: This randomized phase III trial is studying giving combination chemotherapy before and after surgery to see how well it works compared to giving combination chemotherapy after surgery in treating patients with colorectal cancer with liver metastases that could be removed by surgery.
Primary Outcome
Time to recurrence or death
Interventions
- PROCEDURE Postoperative chemotherapy
- PROCEDURE Perioperative chemotherapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2010-08 |
| Est. Completion | 2011-12 |
| Phase | Phase 3 |
Why NCT01189227 stopped before completion
NCT01189227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Postoperative chemotherapy is the first listed.
NCT01189227 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01189227 about?
NCT01189227 is a clinical study titled "Combination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By Surgery". RATIONALE: Drugs used in chemotherapy work in different ways to kill tumor cells or stop them from growing. Giving combination chemotherapy before surgery may make the tumor smaller and reduce the amount of normal tissue that needs to be removed. Giving combination chemotherapy after surgery may kil...
What is the current status of trial NCT01189227?
This trial is currently terminated. It is a Phase 3 study. The enrollment target is 9 participants. The study started on 2010-08. Estimated completion is 2011-12.
What interventions are being tested in trial NCT01189227?
The interventions under investigation include: Postoperative chemotherapy (PROCEDURE), Perioperative chemotherapy (PROCEDURE).
Who is sponsoring clinical trial NCT01189227?
This trial is sponsored by NSABP Foundation, which has 44 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01189227's enrollment target sits among peer trials
9 1992nd of 2000 higher than 8 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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