Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01188226 · ClinicalTrials.gov registry record · NA

Wear Characteristics of Denture Teeth

A NA study, sponsored by University of California, Los Angeles.

Terminated
Registry status
NA
Development phase
10
Enrollment target

NCT01188226: Clinical Trial NA study, sponsored by University of California, Los Angeles.

NCT01188226 is a NA study that was terminated before completion, run by University of California, Los Angeles. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01188226, a NA study, was terminated before completion, sponsored by University of California, Los Angeles.

TERMINATED
Registry status
NA
Development phase
10 participants
Enrollment target

Study Summary

The majority of teeth utilized in the fabrication of conventional complete dentures are made of acrylic resins. These acrylic teeth provide increased bond strength to the denture base and are much easier to adjust for correct denture occlusion compared to teeth made of harder materials, such as porcelain. However, the acrylic teeth will wear faster than the porcelain teeth, leading to alterations in how the teeth contact each other if the denture is not replaced periodically (typically every 5-8 years). With the increase in biting and chewing forces that can be achieved during function with dentures supported by dental implants, the rate of tooth wear may be increased, leading to more frequent need for replacement of the prosthesis. Acrylic teeth made of nano hybrid composite material (NHC) potentially offer greater wear resistance and aesthetic characteristics. The NHC teeth employ a wide range of fillers, including highly cross-linked organic macrofillers, high-density inorganic microfillers and silanized silica based nanofillers. The macrofillers are, to a large part, responsible for the adequate strength and color-stability of the teeth, whereas the microfillers improve the wear resistance. The nanofillers offer fundamentally different optical behaviour from those of larger fillers, improving light reflection without lowering the translucency. This offers additional opportunities in the development of composite teeth, which have to exhibit lifelike aesthetics and translucency. These teeth made of nano-particles and hybrid composites can be made with two different techniques, one where the materials are pressed together and another using an injection technique. The injection method has been found to have better aesthetic results, but resistance to wear in clinical use has not been established. The purpose of this study is to evaluate the wear characteristics of new resin denture teeth (nano particles - hybrid composite) made by an injection technique. Twenty-fou

Primary Outcome

Clinical evaluation of posterior wear location (right, left, equal).

Interventions

  • DEVICE Denture teeth

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2010-08
Est. Completion 2015-06
Phase NA

Why NCT01188226 stopped before completion

NCT01188226 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 1 intervention - of which Denture teeth is the first listed.

NCT01188226 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01188226 about?

NCT01188226 is a clinical study titled "Wear Characteristics of Denture Teeth". The majority of teeth utilized in the fabrication of conventional complete dentures are made of acrylic resins. These acrylic teeth provide increased bond strength to the denture base and are much easier to adjust for correct denture occlusion compared to teeth made of harder materials, such as porc...

What is the current status of trial NCT01188226?

This trial is currently terminated. It is a NA study. The enrollment target is 10 participants. The study started on 2010-08. Estimated completion is 2015-06.

What interventions are being tested in trial NCT01188226?

The interventions under investigation include: Denture teeth (DEVICE).

Who is sponsoring clinical trial NCT01188226?

This trial is sponsored by University of California, Los Angeles, which has 897 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01188226's enrollment target sits among peer trials

10 1927th of 2000 higher than 26 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00623389 · 10 participants · NA

    Evaluation of an Advanced Lower Extremity Neuroprostheses

  • NCT01241864 · 10 participants · Phase 2

    Islet Transplantation in Type 1 Diabetic Kidney Allograft

  • NCT01293214 · 10 participants · NA

    Vascularized Composite Allotransplantation for Multiple Extremity Amputations

  • NCT01474148 · 10 participants · NA

    A Neuroprosthesis for Seated Posture and Balance

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Source: ClinicalTrials.gov NCT01188226, the US trial registry maintained by the National Library of Medicine. NCT01188226 (small enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.