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NCT01187836 · ClinicalTrials.gov registry record · Phase 1
Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure
A Phase 1 study, sponsored by Trevena.
- Completed
- Registry status
- Phase 1
- Development phase
- 33
- Enrollment target
NCT01187836: Completed Phase 1 study, sponsored by Trevena.
NCT01187836 is a Phase 1 study that has completed, run by Trevena. The registered enrollment target is 33 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (45% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01187836, a Phase 1 study, has completed, sponsored by Trevena.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 33 participants
- Enrollment target
Study Summary
In this study, TRV120027 (or a placebo) intravenous infusion will be given to people with heart failure to learn about the effects of TRV120027. The results of this study will help choose the proper range of TRV120027 doses to use in future research studies involving patients with acute decompensated heart failure.
Primary Outcome
The effect of TRV120027 on pulmonary capillary wedge pressure will be compared to baseline and to placebo at multiple measurement time points during the 14 hour infusion and for 4 hours after discontinuation of the infusion.
Interventions
- DRUG Placebo
- DRUG TRV120027
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2010-12 |
| Est. Completion | 2012-03 |
| Phase | Phase 1 |
What the finished NCT01187836 record still lists
NCT01187836 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (45% lower).
The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.
NCT01187836 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01187836 about?
NCT01187836 is a clinical study titled "Study to Evaluate the Effects of TRV120027 in Patients With Heart Failure". In this study, TRV120027 (or a placebo) intravenous infusion will be given to people with heart failure to learn about the effects of TRV120027. The results of this study will help choose the proper range of TRV120027 doses to use in future research studies involving patients with acute decompensate...
What is the current status of trial NCT01187836?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 33 participants. The study started on 2010-12. Estimated completion is 2012-03.
What interventions are being tested in trial NCT01187836?
The interventions under investigation include: Placebo (DRUG), TRV120027 (DRUG).
Who is sponsoring clinical trial NCT01187836?
This trial is sponsored by Trevena, which has 15 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01187836's enrollment target sits among peer trials
33 1280th of 2000 higher than 705 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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