Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT01183065 · ClinicalTrials.gov registry record · Phase 2

Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)

A Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

Completed
Registry status
Phase 2
Development phase
13
Enrollment target

NCT01183065: Completed Phase 2 study, sponsored by Memorial Sloan Kettering Cancer Center.

NCT01183065 is a Phase 2 study that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 13 participants. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT01183065, a Phase 2 study, has completed, sponsored by Memorial Sloan Kettering Cancer Center.

COMPLETED
Registry status
Phase 2
Development phase
13 participants
Enrollment target

Study Summary

The purpose of this study is to find out if the experimental drug pralatrexate with the vitamins folic acid and vitamin B12 might be an effective treatment for head and neck cancer. The reason we are doing this study is because another drug called methotrexate has been used for a long time to treat head and neck cancer patients. Pralatrexate was designed by scientists to be a new drug that works better than methotrexate. Laboratory studies have shown that pralatrexate works better than methotrexate at killing cancer cells. Pralatrexate has already been studied in patients with other types of cancers, such as lymphoma and lung cancer. The results from those studies were promising. Pralatrexate was recently approved by the Food and Drug Administration (FDA) as a new treatment for a cancer called peripheral T cell lymphoma.

Interventions

  • DRUG Pralatrexate With Vitamin B12 and Folic Acid

Trial Details

FieldValue
Enrollment Target 13 participants
Start Date 2010-08
Est. Completion 2014-04
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT01183065

The ClinicalTrials.gov registry entry for NCT01183065 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 13 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Pralatrexate With Vitamin B12 and Folic Acid is the first listed.

NCT01183065 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01183065 about?

NCT01183065 is a clinical study titled "Study of Pralatrexate With Vitamin B12 and Folic Acid Supplementation for Previously Treated Recurrent or Metastatic Head and Neck Squamous Cell Cancer (HNSCC)". The purpose of this study is to find out if the experimental drug pralatrexate with the vitamins folic acid and vitamin B12 might be an effective treatment for head and neck cancer. The reason we are doing this study is because another drug called methotrexate has been used for a long time to treat ...

What is the current status of trial NCT01183065?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 13 participants. The study started on 2010-08. Estimated completion is 2014-04.

What interventions are being tested in trial NCT01183065?

The interventions under investigation include: Pralatrexate With Vitamin B12 and Folic Acid (DRUG).

Who is sponsoring clinical trial NCT01183065?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.