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NCT01182558 · ClinicalTrials.gov registry record · NA

The Effect of Prior Muscle Activation on the Compound Muscle Action Potential (CMAP)

A NA study, sponsored by Loma Linda University.

Completed
Registry status
NA
Development phase
6
Enrollment target

NCT01182558: Completed NA study, sponsored by Loma Linda University.

NCT01182558 is a NA study that has completed, run by Loma Linda University. The registered enrollment target is 6 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01182558, a NA study, has completed, sponsored by Loma Linda University.

COMPLETED
Registry status
NA
Development phase
6 participants
Enrollment target

Study Summary

The purpose of this investigator-initiated study is to determine the effect of prior muscle activation on the response obtained by nerve conduction studies (the compound muscle action potential \[CMAP\]) looking at the amplitude, area, and duration of the CMAP and evaluating the length of time the CMAP is larger than at baseline. On the opposite side, the corresponding CMAP will be tested periodically, but there will be no muscle activation on that side. Null Hypothesis: While controlling all possible technical and other known physiological variables, prior activation of a muscle has no effect on the amplitude and area of the compound muscle action potential (CMAP); and the CMAP does not change over time in the relaxed muscle (on the opposite side). The investigators suspect that there is an effect of prior activation of the muscle on the subsequent CMAP recorded from that muscle.

Primary Outcome

Amplitude (baseline to negative peak) of the compound muscle action potential (CMAP) recorded from the hypothenar eminence after stimulation of the ulnar nerve at the wrist

Interventions

  • OTHER Hypothenar muscle activation--maximum, voluntary, isometric
  • OTHER Thenar muscle activation--maximum, voluntary, isometric
  • OTHER EDB muscle activation--maximum, voluntary, isometric
  • OTHER Relaxation of muscle

Trial Details

FieldValue
Enrollment Target 6 participants
Start Date 2010-10
Est. Completion 2019-08
Phase NA
Loma Linda University

237 total trials

What the finished NCT01182558 record still lists

NCT01182558 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).

The record links to 0 conditions, and to 4 interventions - of which Hypothenar muscle activation--maximum, voluntary, isometric is the first listed.

NCT01182558 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01182558 about?

NCT01182558 is a clinical study titled "The Effect of Prior Muscle Activation on the Compound Muscle Action Potential (CMAP)". The purpose of this investigator-initiated study is to determine the effect of prior muscle activation on the response obtained by nerve conduction studies (the compound muscle action potential \[CMAP\]) looking at the amplitude, area, and duration of the CMAP and evaluating the length of time the C...

What is the current status of trial NCT01182558?

This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2010-10. Estimated completion is 2019-08.

What interventions are being tested in trial NCT01182558?

The interventions under investigation include: Hypothenar muscle activation--maximum, voluntary, isometric (OTHER), Thenar muscle activation--maximum, voluntary, isometric (OTHER), EDB muscle activation--maximum, voluntary, isometric (OTHER), Relaxation of muscle (OTHER).

Who is sponsoring clinical trial NCT01182558?

This trial is sponsored by Loma Linda University, which has 237 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01182558's enrollment target sits among peer trials

6 1983rd of 2000 higher than 13 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01182558, the US trial registry maintained by the National Library of Medicine. NCT01182558 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.