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NCT01179282 · ClinicalTrials.gov registry record · NA
Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients
A NA study, sponsored by University of South Florida.
- Completed
- Registry status
- NA
- Development phase
- 42
- Enrollment target
NCT01179282 is a NA study that has completed, run by University of South Florida. The registered enrollment target is 42 participants.
The verdict
NCT01179282, a NA study, has completed, sponsored by University of South Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
Study Summary
Subjects who have a clinical history of perennial rhinitis symptoms associated with dust exposure or not associated with other perennial allergens, will have a positive challenge with Dermatophagoides pteronyssinus. Subjects will be ppt negative and intradermal skin test positive to Dust p Challenges will be performed with placebo or Dp extract three times daily each for 2 weeks. Primary endpoint after nasal challenge with Dust p Mean Symptom score increase by greater than or equal to 2 from baseline. Secondary Outcomes Mean decrease in PNIF by greater than 15percent from baseline. Mean increase in nasal lavage PGD2 and ECP by greater than 15percent from baseline levels. Correlation between the orthogonol diameter of the wheal and flare of the intradermal skin test and the degree of symptom worsening during the nasal challenge. These results will provide evidence for the continued use of the intradermal skin test in evaluating allergic rhinitis.
Interventions
- BIOLOGICAL dust mite extract or placebo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2009-06 |
| Est. Completion | 2012-12 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01179282
The ClinicalTrials.gov registry entry for NCT01179282 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of South Florida, which has 252 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which dust mite extract or placebo is the first listed.
NCT01179282 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT01179282 about?
NCT01179282 is a clinical study titled "Repeated Nasal Challenge in Skin Prick-puncture Negative and Intradermal Positive Dust Mite Allergic Rhinitis Patients". Subjects who have a clinical history of perennial rhinitis symptoms associated with dust exposure or not associated with other perennial allergens, will have a positive challenge with Dermatophagoides pteronyssinus. Subjects will be ppt negative and intradermal skin test positive to Dust p Challenge...
What is the current status of trial NCT01179282?
This trial is currently completed. It is a NA study. The enrollment target is 42 participants. The study started on 2009-06. Estimated completion is 2012-12.
What interventions are being tested in trial NCT01179282?
The interventions under investigation include: dust mite extract or placebo (BIOLOGICAL).
Who is sponsoring clinical trial NCT01179282?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
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