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NCT01178320 · ClinicalTrials.gov registry record
Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)
A clinical trial, sponsored by University of Washington.
- Completed
- Registry status
- 230
- Enrollment target
NCT01178320: Completed study, sponsored by University of Washington.
NCT01178320 is a clinical trial that has completed, run by University of Washington. The registered enrollment target is 230 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01178320 has completed, sponsored by University of Washington.
- COMPLETED
- Registry status
- 230 participants
- Enrollment target
Study Summary
Heart attacks and strokes caused by the unstable atherosclerotic plaques remain the leading cause of death in the United States. Unstable plaques often have more fat than stable plaques. This study will investigate if a treatment with LDL-lowering plus HDL-raising compared with LDL-lowering alone would more effectively reduce the plaque fat content assessed by magnetic resonance imaging (MRI), therefore, further reducing heart attacks and strokes.
Primary Outcome
To test the primary hypothesis that compared with LDL-lowering alone, intensive LDL-lowering plus HDL-raising therapy decreases the mean plaque lipid composition in carotid arteries assessed by MRI.
Interventions
- DRUG Simvastatin, simvastatin plus extended-release niacin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 230 participants |
| Start Date | 2008-03 |
| Est. Completion | 2015-02 |
What the finished NCT01178320 record still lists
NCT01178320 is an observational study that tracks outcomes without assigning an intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 1 intervention - of which Simvastatin, simvastatin plus extended-release niacin is the first listed.
NCT01178320 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01178320 about?
NCT01178320 is a clinical study titled "Carotid Plaque Characteristics by MRI in AIM-HIGH (Carotid MRI Substudy)". Heart attacks and strokes caused by the unstable atherosclerotic plaques remain the leading cause of death in the United States. Unstable plaques often have more fat than stable plaques. This study will investigate if a treatment with LDL-lowering plus HDL-raising compared with LDL-lowering alone wo...
What is the current status of trial NCT01178320?
This trial is currently completed. The enrollment target is 230 participants. The study started on 2008-03. Estimated completion is 2015-02.
What interventions are being tested in trial NCT01178320?
The interventions under investigation include: Simvastatin, simvastatin plus extended-release niacin (DRUG).
Who is sponsoring clinical trial NCT01178320?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
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