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NCT01175018 · ClinicalTrials.gov registry record · Phase 2

Anakinra to Prevent Adverse Post-infarction Remodeling (2)

A Phase 2 study, sponsored by Virginia Commonwealth University.

Completed
Registry status
Phase 2
Development phase
30
Enrollment target

NCT01175018 is a Phase 2 study that has completed, run by Virginia Commonwealth University. The registered enrollment target is 30 participants.

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The verdict

NCT01175018, a Phase 2 study, has completed, sponsored by Virginia Commonwealth University.

COMPLETED
Registry status
Phase 2
Development phase
30 participants
Enrollment target

Study Summary

Acute myocardial infarction (AMI) remains a major cause of morbidity and mortality. Many patients die early during the course, and those who survive are at risk for dying late from adverse cardiac remodeling and heart failure. The initial ischemic damage to the myocardium initiates an intense inflammatory response in promoting further cardiac dysfunction and heart failure. The investigators propose that an antiinflammatory strategy based on blockade of Interleukin-1 will quench the inflammatory response and lead to a more favorable cardiac remodeling process.

Interventions

  • DRUG Placebo
  • DRUG Anakinra

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2010-07
Est. Completion 2012-12
Phase Phase 2

Sponsor

Virginia Commonwealth University

558 total trials

What the Registry Record Tells You About NCT01175018

The ClinicalTrials.gov registry entry for NCT01175018 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Virginia Commonwealth University, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT01175018 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT01175018 about?

NCT01175018 is a clinical study titled "Anakinra to Prevent Adverse Post-infarction Remodeling (2)". Acute myocardial infarction (AMI) remains a major cause of morbidity and mortality. Many patients die early during the course, and those who survive are at risk for dying late from adverse cardiac remodeling and heart failure. The initial ischemic damage to the myocardium initiates an intense infla...

What is the current status of trial NCT01175018?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2010-07. Estimated completion is 2012-12.

What interventions are being tested in trial NCT01175018?

The interventions under investigation include: Placebo (DRUG), Anakinra (DRUG).

Who is sponsoring clinical trial NCT01175018?

This trial is sponsored by Virginia Commonwealth University, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.