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NCT01171131 · ClinicalTrials.gov registry record
A Pilot Study to Identify Biomarkers Associated With Chronic Traumatic Brain Injury
A clinical trial, sponsored by The University of Texas Health Science Center, Houston.
- Completed
- Registry status
- 96
- Enrollment target
NCT01171131: Completed study, sponsored by The University of Texas Health Science Center, Houston.
NCT01171131 is a clinical trial that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 96 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01171131 has completed, sponsored by The University of Texas Health Science Center, Houston.
- COMPLETED
- Registry status
- 96 participants
- Enrollment target
Study Summary
The aim of this research is to determine if the biological fluids (blood/saliva) from chronic brain-injured patients (both blast and non-penetrating TBI) contain reproducible protein markers. To accomplish this two populations of chronic TBI patients who are receiving treatment at The Institute for Research and Rehabilitation (TIRR): blast injury victims and non-penetrating TBI will be studied. Using multiple proteomic approaches including mass spectrometry, multiplex ELISAs, and antibody microarrays, as well as RNA profiling, the investigators aim to identify biomarkers in the blood/saliva of patients suffering from chronic TBI and to determine the similarities/differences between the blast and non-penetrating injury groups. Identification of these biochemical changes will give insight into the long-lasting changes associated with head injury, and may identify new targets for treating the associated pathologies.
Primary Outcome
The aim is to identify biomarkers in the blood of patients suffering from chronic TBI and to determine the similarities/differences between the blast and non-penetrating injury groups.
Interventions
- OTHER Blood/saliva sampling
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 96 participants |
| Start Date | 2010-04 |
| Est. Completion | 2016-03-03 |
What the finished NCT01171131 record still lists
NCT01171131 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 96 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Blood/saliva sampling is the first listed.
NCT01171131 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01171131 about?
NCT01171131 is a clinical study titled "A Pilot Study to Identify Biomarkers Associated With Chronic Traumatic Brain Injury". The aim of this research is to determine if the biological fluids (blood/saliva) from chronic brain-injured patients (both blast and non-penetrating TBI) contain reproducible protein markers. To accomplish this two populations of chronic TBI patients who are receiving treatment at The Institute for ...
What is the current status of trial NCT01171131?
This trial is currently completed. The enrollment target is 96 participants. The study started on 2010-04. Estimated completion is 2016-03-03.
What interventions are being tested in trial NCT01171131?
The interventions under investigation include: Blood/saliva sampling (OTHER).
Who is sponsoring clinical trial NCT01171131?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
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