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NCT01171118 · ClinicalTrials.gov registry record · NA
Phamacological Reversal of Airway Instability During Sedation
A NA study of Upper Airway Obstruction, sponsored by University of Rochester.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT01171118: Completed NA study of Upper Airway Obstruction, sponsored by University of Rochester.
NCT01171118 is a NA study of Upper Airway Obstruction that has completed, run by University of Rochester. The registered enrollment target is 10 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01171118, a NA study of Upper Airway Obstruction, has completed, sponsored by University of Rochester.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
The investigators are attempting to demonstrate a decrease in the frequency and severity of sedation-induced respiratory arrhythmias(central and obstructive apneas) with pharmacological pre-treatment in this pilot project and then eventually to understand the mechanisms behind this decrease. The efficacy and mechanisms of these treatments, while evaluated during sleep in Obstructed Sleep Apnea (OSA) patients, have not been systematically studied during sedation in either normal subjects or OSA patients. The agent to be assessed in this study in physostigmine versus placebo.
Primary Outcome
This is a standard metric used to describe severity of disordered breathing during sleep.Normal healthy subjects would have an AHI value of zero during sleep. Mild disordered breathing would correspond to a value of 5 to 10 events per hours; moderate 10-25; severe would be over 25
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Oxygen
- DRUG Physostigmine
Study Locations (1)
New York
- University of Rochester Medical Center - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2009-08 |
| Est. Completion | 2011-08 |
| Phase | NA |
What the finished NCT01171118 record still lists
NCT01171118 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Upper Airway Obstruction appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.
NCT01171118 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01171118 about?
NCT01171118 is a clinical study titled "Phamacological Reversal of Airway Instability During Sedation". The investigators are attempting to demonstrate a decrease in the frequency and severity of sedation-induced respiratory arrhythmias(central and obstructive apneas) with pharmacological pre-treatment in this pilot project and then eventually to understand the mechanisms behind this decrease. The eff...
What is the current status of trial NCT01171118?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2009-08. Estimated completion is 2011-08.
What conditions does trial NCT01171118 study?
This clinical trial studies the following conditions: Upper Airway Obstruction.
What interventions are being tested in trial NCT01171118?
The interventions under investigation include: Placebo (DRUG), Oxygen (DRUG), Physostigmine (DRUG).
Who is sponsoring clinical trial NCT01171118?
This trial is sponsored by University of Rochester, which has 636 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01171118 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01171118's enrollment target sits among peer trials
10 1927th of 2000 higher than 26 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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